Acute Liver Failure (ALF), also known as Fulminant Hepatic Failure or Acute Hepatic Failure, is a severe condition requiring prompt diagnosis and treatment. This page provides critical information for healthcare professionals on clinical documentation, medical coding, and diagnostic criteria related to Acute Liver Failure. Learn about the signs, symptoms, and management of ALF to improve patient care and ensure accurate clinical documentation for coding and billing purposes. Find resources for healthcare providers, including information on ICD-10 codes and best practices for documenting Acute Hepatic Failure in medical records.
Also known as
Acute and subacute liver failure
Covers acute liver failure, including fulminant hepatic failure.
Unspecified jaundice
May be relevant if liver failure presents with jaundice.
Ascites
Covers ascites, a possible complication of liver failure.
Follow this step-by-step guide to choose the correct ICD-10 code.
Is the liver failure acute?
Yes
Is it due to drug/toxin?
No
Do not code as acute liver failure. Consider other liver disease codes.
When to use each related code
| Description |
|---|
| Sudden, severe liver malfunction. |
| Chronic liver damage leading to scarring and dysfunction. |
| Liver inflammation caused by various factors. |
Coding acute liver failure without documenting the underlying cause (e.g., viral hepatitis, drug toxicity) leads to inaccurate coding and affects DRG assignment.
Missing documentation of pre-existing conditions like cirrhosis or hepatitis impacts severity scores and reimbursement. Comprehensive CDI is crucial.
Failing to distinguish between acute liver failure with or without liver transplant consideration affects resource utilization and quality metrics reporting.
Q: What are the key differentiating factors in diagnosing acute liver failure (ALF) versus other forms of liver dysfunction, such as chronic liver disease or acute-on-chronic liver failure (ACLF)?
A: Differentiating acute liver failure (ALF) from chronic liver disease, acute-on-chronic liver failure (ACLF), and other liver dysfunction requires a multifaceted approach. ALF is characterized by the rapid development of hepatic encephalopathy (HE) within 26 weeks of the onset of jaundice in a patient without pre-existing liver disease. This contrasts with chronic liver disease, which develops slowly over time, often with a known etiology like viral hepatitis or alcohol abuse. ACLF, on the other hand, represents acute deterioration in patients with pre-existing chronic liver disease, usually triggered by a precipitating event like infection or gastrointestinal bleeding. Key distinguishing factors include the presence or absence of pre-existing liver disease, the timescale of symptom onset, the presence of coagulopathy (INR >1.5), and the severity of hepatic encephalopathy. Explore how a thorough patient history, physical exam, and laboratory testing including liver function tests, coagulation profile, and ammonia levels can aid in accurate diagnosis and guide appropriate management. Consider implementing standardized diagnostic criteria for ALF, ACLF, and chronic liver disease to improve consistency and accuracy in clinical practice.
Q: What are the most effective strategies for managing hepatic encephalopathy in a patient with acute liver failure, considering its rapid progression and potential for severe complications?
A: Managing hepatic encephalopathy (HE) in acute liver failure (ALF) is crucial due to its rapid progression and potential for severe complications, including cerebral edema and brain herniation. Treatment strategies focus on identifying and addressing precipitating factors such as infection, gastrointestinal bleeding, constipation, and electrolyte imbalances. Non-absorbable disaccharides like lactulose are commonly used to reduce ammonia levels in the gut. Rifaximin, an antibiotic, can also be added to target ammonia-producing bacteria. Close monitoring of neurological status is essential, and measures like intracranial pressure monitoring may be considered in severe cases. Learn more about the latest guidelines for managing HE in ALF, including recommendations for optimizing nutrition and addressing potential complications like cerebral edema. Consider implementing a multidisciplinary approach involving hepatologists, neurologists, and critical care specialists to provide comprehensive care for these complex patients.
Patient presents with acute liver failure (ALF), also known as fulminant hepatic failure or acute hepatic failure, manifesting as [Specific symptom e.g., jaundice, encephalopathy, coagulopathy]. Onset of symptoms occurred [Timeframe e.g., two weeks ago] and progressed [Description of progression e.g., rapidly over the past few days]. Patient denies [Pertinent negatives e.g., history of chronic liver disease, excessive alcohol consumption] but reports [Relevant positives e.g., recent acetaminophen overdose, exposure to toxins, viral infection]. Physical examination reveals [Clinical findings e.g., hepatomegaly, ascites, asterixis]. Laboratory findings demonstrate elevated liver enzymes (AST, ALT), prolonged prothrombin time (PT), and elevated bilirubin levels, consistent with the diagnosis of acute liver failure. Differential diagnosis includes other causes of acute hepatic injury such as viral hepatitis, drug-induced liver injury, and autoimmune hepatitis. Initial treatment includes [Specific treatments e.g., N-acetylcysteine if acetaminophen overdose is suspected, supportive care with fluid management and electrolyte correction]. Patient requires close monitoring for hepatic encephalopathy and other complications of acute liver failure. Prognosis and treatment plan will be discussed with the patient and family, including consideration for liver transplantation if indicated. ICD-10 code K72.01 (Acute and subacute hepatic failure) is documented for medical billing and coding purposes. Further investigations are ongoing to determine the underlying etiology of acute liver failure and guide further management.