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D63.1
ICD-10-CM
Anemia of Chronic Disease

Understand Anemia of Chronic Disease (ACD), also known as Anemia of Inflammation or Anemia of Chronic Illness. This resource provides information on diagnosis, clinical documentation, and medical coding for anemia chronic disease, crucial for healthcare professionals and medical coding specialists. Learn about the connection between ACD and inflammation, relevant lab values, and best practices for accurate medical record keeping.

Also known as

Anemia of Inflammation
Anemia of Chronic Illness
anemia chronic disease
+1 more

Diagnosis Snapshot

Key Facts
  • Definition : Anemia caused by chronic inflammation, infection, or malignancy, impairing iron utilization.
  • Clinical Signs : Fatigue, weakness, shortness of breath, pale skin, headaches, dizziness.
  • Common Settings : Rheumatoid arthritis, chronic kidney disease, inflammatory bowel disease, cancer.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC D63.1 Coding
D63.0

Anemia in chronic diseases classified elsewhere

Anemia associated with various chronic conditions.

D50-D53

Nutritional anemias

Anemias caused by dietary deficiencies.

D60-D64

Aplastic and other anemias

Covers diverse anemias like aplastic and sideroblastic.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the anemia associated with a chronic inflammatory, infectious, or malignant condition?

  • Yes

    Is the underlying condition documented?

  • No

    Do NOT code as anemia of chronic disease. Consider other anemia diagnoses.

Code Comparison

Related Codes Comparison

When to use each related code

Description
Low red blood cells due to chronic disease.
Low iron, leading to reduced red blood cell production.
Vitamin B12 deficiency impairs red blood cell development.

Documentation Best Practices

Documentation Checklist
  • Document underlying chronic disease (ICD-10 code).
  • Specify type of anemia (e.g., normocytic, normochromic).
  • Hb/Hct, RBC indices, iron studies results.
  • Rule out other anemia causes (iron deficiency, B12/folate).
  • Document treatment plan and rationale (if applicable).

Coding and Audit Risks

Common Risks
  • Unspecified Anemia Type

    Coding anemia of chronic disease without specifying the underlying etiology (e.g., rheumatoid arthritis) leads to inaccurate reporting and potential DRG misassignment.

  • Confusing with Iron Deficiency

    Misdiagnosing anemia of chronic disease as iron deficiency anemia can lead to inappropriate treatment and inaccurate quality metrics related to anemia management.

  • Lack of Supporting Documentation

    Insufficient documentation of the chronic condition causing the anemia may lead to coding queries, denials, and compliance issues during audits.

Mitigation Tips

Best Practices
  • Treat underlying disease. Code ICD-10 D63.0.
  • Document iron studies, ESR, CRP. CDI: specificity.
  • Erythropoiesis-stimulating agents if indicated. HCC coding guidelines.
  • Optimize nutrition, hydration status. ICD-10-CM coding best practices.
  • Transfusion rarely needed. Document rationale for HCC compliance.

Clinical Decision Support

Checklist
  • Verify underlying chronic disease diagnosis (e.g., ICD-10 D63.0, rheumatoid arthritis).
  • Confirm normocytic or microcytic anemia with CBC and peripheral smear review.
  • Check serum iron, ferritin, transferrin saturation, and total iron-binding capacity.
  • Exclude other anemia causes (iron deficiency, B12/folate, hemolysis) via appropriate testing.

Reimbursement and Quality Metrics

Impact Summary
  • Anemia of Chronic Disease (Anemia of Inflammation, Anemia of Chronic Illness) reimbursement hinges on accurate ICD-10-CM coding (e.g., N62.81) for optimal claims processing.
  • Coding Anemia of Chronic Disease impacts quality metrics related to patient blood management, potentially affecting hospital value-based purchasing.
  • Accurate Anemia of Chronic Disease coding supports appropriate resource utilization, impacting hospital case mix index and DRG assignment.
  • Proper documentation and coding of Anemia of Chronic Disease improves data integrity for hospital reporting and quality improvement initiatives.

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Frequently Asked Questions

Common Questions and Answers

Q: How can I differentiate Anemia of Chronic Disease (ACD) from Iron Deficiency Anemia (IDA) in patients with chronic inflammatory conditions?

A: Differentiating Anemia of Chronic Disease (ACD) from Iron Deficiency Anemia (IDA) in patients with chronic inflammatory conditions can be challenging due to overlapping symptoms. Key distinguishing features include: serum ferritin levels (typically normal or elevated in ACD, low in IDA), transferrin saturation (low in both, but often higher in ACD), total iron-binding capacity (TIBC) (low in ACD, high in IDA), and soluble transferrin receptor (sTfR) (normal or slightly elevated in ACD, elevated in IDA). Furthermore, evaluating the patient's inflammatory markers (e.g., C-reactive protein, erythrocyte sedimentation rate) can help identify underlying inflammation contributing to ACD. Bone marrow examination, though less commonly performed, may reveal increased iron stores in ACD despite reduced erythropoiesis. Consider implementing a diagnostic algorithm incorporating these parameters for accurate differentiation and targeted treatment. Explore how a comprehensive approach to iron studies interpretation can improve diagnostic accuracy in these complex cases.

Q: What are the evidence-based management strategies for Anemia of Chronic Disease (ACD) in patients with rheumatoid arthritis?

A: Managing Anemia of Chronic Disease (ACD) in patients with rheumatoid arthritis requires a multi-faceted approach. First, prioritize optimizing treatment of the underlying rheumatoid arthritis, as controlling the inflammatory process can improve anemia. While iron supplementation is generally not recommended in ACD due to impaired iron utilization and potential risks, it may be considered in select cases with true iron deficiency coexisting with ACD, after careful evaluation of iron indices. Erythropoiesis-stimulating agents (ESAs) like erythropoietin or darbepoetin alfa can be beneficial, particularly in patients with moderate to severe anemia and inadequate response to disease-modifying antirheumatic drugs (DMARDs). However, ESA use needs careful consideration of potential risks, including cardiovascular events. Learn more about the potential benefits and risks of ESAs in ACD management to individualize patient care. Consider implementing a treatment plan that balances managing the underlying inflammatory condition and addressing the anemia itself.

Quick Tips

Practical Coding Tips
  • Code D63.8 for ACD unspecified
  • Document underlying chronic disease
  • Query physician if etiology unclear
  • Consider secondary codes for manifestation
  • Check payer guidelines for ACD coding

Documentation Templates

Patient presents with signs and symptoms suggestive of anemia of chronic disease (ACD), also referred to as anemia of inflammation or anemia of chronic illness.  The patient reports fatigue, weakness, and decreased exercise tolerance.  Physical examination reveals pallor.  Relevant laboratory findings include a normocytic or slightly microcytic anemia with a low hemoglobin and hematocrit.  Serum iron levels are low, while ferritin levels are normal or elevated, differentiating this from iron deficiency anemia.  Total iron binding capacity (TIBC) is typically low or normal.  The underlying chronic disease, diagnosed as [Insert specific chronic disease e.g., rheumatoid arthritis, chronic kidney disease, inflammatory bowel disease], is considered the etiologic factor contributing to the anemia.  The patient's current medication list includes [List current medications].  Differential diagnoses considered included iron deficiency anemia, thalassemia, and sideroblastic anemia.  Based on the clinical presentation, laboratory results, and underlying chronic disease, the diagnosis of anemia of chronic disease is established.  The treatment plan will focus on managing the underlying chronic disease.  Further laboratory monitoring of hemoglobin, hematocrit, iron studies, and inflammatory markers will be performed to assess response to treatment.  Patient education provided on anemia of chronic disease, its relationship to the underlying condition, and the importance of adherence to the treatment plan for the primary disease.  ICD-10 code D63.8 (Anemia in other chronic diseases classified elsewhere) is applicable.  Follow-up scheduled in [ timeframe e.g., four weeks] to reassess the anemia and the underlying condition.
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