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Z13.6
ICD-10-CM
C-Reactive Protein Screening

Understand C-Reactive Protein (CRP) screening, including hs-CRP, and its role in healthcare. Learn about CRP test interpretation, clinical documentation best practices, and medical coding for accurate billing. Find information on elevated CRP levels, normal ranges, and the significance of CRP in diagnosing inflammation and guiding treatment decisions.

Also known as

CRP Test
hs-CRP Screening

Diagnosis Snapshot

Key Facts
  • Definition : Blood test measuring C-reactive protein, an inflammation marker.
  • Clinical Signs : Fever, swelling, pain, redness, fatigue. Often nonspecific.
  • Common Settings : Primary care, urgent care, hospitals for infection or inflammation monitoring.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC Z13.6 Coding
R74.0

Abnormal findings of CRP

Elevated or abnormal C-reactive protein levels.

R79.89

Other specified abnormal findings

May be used for CRP screening if no other code fits.

Z01.80

Encounter for other preprocedural exam

Use if CRP is part of pre-op or general health check.

Z13.820

Encounter for screening for oth disord

For general health screening including CRP testing.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is CRP screening for risk assessment?

  • Yes

    Is it for cardiac risk?

  • No

    Is it for monitoring inflammation?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Measures C-reactive protein levels to detect inflammation.
Measures erythrocyte sedimentation rate to detect inflammation.
Measures procalcitonin levels to assess risk of severe bacterial infections.

Documentation Best Practices

Documentation Checklist
  • Document indication for CRP test (e.g., infection, inflammation)
  • Record CRP level (mg/L) and units
  • Specify test type: standard CRP or high-sensitivity hs-CRP
  • Note patient symptoms related to inflammation (e.g., fever, swelling)
  • Document interpretation of CRP results and clinical significance

Coding and Audit Risks

Common Risks
  • CRP Specificity

    Non-specific marker, coding requires clear documentation linking CRP elevation to a diagnosed condition to avoid misinterpretation as a standalone diagnosis.

  • hs-CRP vs. CRP

    Incorrect coding between high-sensitivity CRP (hs-CRP) and standard CRP tests. Distinct codes exist and must align with the ordered/performed test.

  • Medical Necessity

    Insufficient documentation supporting medical necessity for CRP screening. Clear indication for the test must be present in the patient record for compliance.

Mitigation Tips

Best Practices
  • Document CRP indication (infection, inflammation, etc.)
  • Code CRP order with correct LOINC and CPT codes
  • Specify hs-CRP for cardiac risk assessment in documentation
  • Ensure medical necessity for CRP testing per payer guidelines
  • Monitor serial CRP results for trending and response to therapy

Clinical Decision Support

Checklist
  • Confirm indication: Infection, inflammation, or CVD risk?
  • Verify no recent trauma or surgery (false positive)
  • Document CRP value and units (mg/L or mg/dL)
  • Correlate CRP with clinical picture and other labs

Reimbursement and Quality Metrics

Impact Summary
  • C-Reactive Protein Screening (CRP Test, hs-CRP Screening) Reimbursement and Quality Metrics Impact Summary
  • ICD-10 coding: Accurate coding maximizes C-Reactive Protein test reimbursement. Common codes include R74.0 (abnormal CRP), I20.9 (angina pectoris, unspecified), M32.11 (SLE with organ or system involvement). Proper coding impacts hospital revenue cycle management and minimizes claim denials.
  • Quality metrics: CRP screening data informs quality reporting programs like HEDIS and MIPS. Accurate documentation and coding contribute to improved performance scores, impacting hospital value-based payments.
  • Hospital reporting: CRP test data enables tracking infection rates, inflammation levels, and cardiovascular risk. This data supports quality improvement initiatives and population health management strategies, ultimately impacting hospital reimbursement linked to performance.
  • Medical billing: Accurate CPT coding (e.g., 86140, 86141) for CRP screening is crucial for proper reimbursement. Clear documentation of medical necessity ensures compliance and reduces claim rejections, optimizing hospital revenue.

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Frequently Asked Questions

Common Questions and Answers

Q: What are the most clinically significant high-sensitivity C-reactive protein (hs-CRP) level interpretations for cardiovascular risk stratification in asymptomatic patients?

A: High-sensitivity C-reactive protein (hs-CRP) levels are a valuable marker for assessing cardiovascular risk in asymptomatic patients. Clinically significant interpretations are generally categorized as follows: low risk (<1.0 mg/L), average risk (1.0-3.0 mg/L), and high risk (>3.0 mg/L). However, it's crucial to remember that hs-CRP is just one piece of the puzzle. Clinical interpretation should always consider the patient's overall risk profile, including traditional risk factors like age, smoking status, family history, lipid levels, and blood pressure. For example, a patient with an hs-CRP of 2.5 mg/L and multiple other risk factors may be considered at higher risk than a patient with the same hs-CRP but no other risk factors. Explore how incorporating hs-CRP into a comprehensive risk assessment can enhance patient management strategies for cardiovascular disease prevention. Consider implementing risk calculators that integrate hs-CRP values to provide personalized risk estimates.

Q: When should I order a C-reactive protein (CRP) test vs. an hs-CRP test, and how do the results inform treatment decisions for suspected infection or inflammation?

A: A standard CRP test is generally used to detect and monitor significant inflammation, such as in acute infections or inflammatory conditions like rheumatoid arthritis. It's less sensitive than an hs-CRP test and may not be useful for subtle inflammatory changes. The hs-CRP test, on the other hand, is designed to measure lower levels of CRP and is primarily used for cardiovascular risk assessment. When an infection is suspected, a standard CRP test can help confirm the presence of inflammation and monitor treatment response. Significantly elevated CRP levels may suggest a bacterial infection or a severe inflammatory response. For chronic inflammatory conditions, serial CRP measurements can help track disease activity and response to therapy. Learn more about the specific CRP and hs-CRP reference ranges used in your laboratory setting, as they may vary slightly. Consider implementing guidelines for interpreting CRP levels in different clinical scenarios to ensure appropriate clinical decision-making.

Quick Tips

Practical Coding Tips
  • Code CRP screenings with 86140
  • Document indication for CRP test
  • Specify hs-CRP for 86705
  • Check payer guidelines for CRP
  • Correlate CRP with clinical findings

Documentation Templates

Patient presents for C-reactive protein (CRP) screening, also known as a CRP test or hs-CRP screening, to assess for systemic inflammation.  The indication for this laboratory test includes evaluation for infection, inflammatory diseases such as rheumatoid arthritis or inflammatory bowel disease, and cardiovascular risk stratification.  The patient's medical history, family history, and current symptoms were reviewed and documented.  Relevant findings include (list pertinent positives and negatives such as fever, fatigue, joint pain, recent infection, family history of heart disease, etc.).  Based on the clinical presentation and risk factors, CRP screening was ordered to aid in diagnosis and management.  Pretest probability for elevated CRP was assessed.  Results of the CRP test will be reviewed upon receipt and will be used in conjunction with other clinical findings to guide further diagnostic testing and treatment planning, if necessary.  Patient education was provided regarding the purpose of CRP screening, the interpretation of results, and potential implications for their overall health.  Follow-up plan and instructions were discussed and documented.  Appropriate CPT and ICD-10 codes will be applied for medical billing and coding purposes.