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R53.82
ICD-10-CM
Chronic Fatigue

Understanding Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME/CFS), requires accurate clinical documentation for diagnosis and medical coding. This page provides information on Chronic Fatigue diagnosis criteria, including symptoms, diagnostic tests, and ICD codes relevant for healthcare professionals documenting ME/CFS in patient records. Learn about Chronic Fatigue management and treatment options for improved patient care and accurate medical billing.

Also known as

Chronic Fatigue Syndrome
Myalgic Encephalomyelitis
ME/CFS

Diagnosis Snapshot

Key Facts
  • Definition : Persistent, unexplained fatigue lasting 6+ months, not relieved by rest, plus other symptoms like post-exertional malaise.
  • Clinical Signs : Fatigue, brain fog, sleep disturbances, muscle pain, headaches, orthostatic intolerance.
  • Common Settings : Primary care, immunology clinics, sleep centers, pain management clinics.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC R53.82 Coding
G93.3

Chronic fatigue syndrome

Significant fatigue not relieved by rest, lasting 6+ months.

R53.83

Other fatigue

Fatigue not otherwise specified, possibly related to chronic conditions.

F48.0

Neurasthenia

Persistent fatigue and weakness, often with mental distress.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Does the patient meet the criteria for ME/CFS?

  • Yes

    Is there documented Post-Exertional Malaise?

  • No

    Is fatigue the primary symptom?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Persistent exhaustion not relieved by rest.
Debilitating fatigue after a viral infection.
Excessive daytime sleepiness and sleep attacks.

Documentation Best Practices

Documentation Checklist
  • Document substantial reduction or impairment in ability to engage in pre-illness levels of occupational, educational, social, or personal activities.
  • Record duration of persistent or relapsing fatigue lasting six months or longer.
  • Document post-exertional malaise (PEM) where physical or mental activity substantially worsens symptoms.
  • Document unrefreshing sleep.
  • Include cognitive impairment or orthostatic intolerance symptoms.

Coding and Audit Risks

Common Risks
  • Unspecified CFS Coding

    Using unspecified codes (e.g., R53.82) when more specific ME/CFS codes (e.g., G93.3) are clinically supported, impacting reimbursement and data accuracy.

  • Comorbidity Overlap

    Miscoding overlapping symptoms (e.g., fibromyalgia, depression) as primary diagnoses instead of secondary to CFS, affecting quality metrics.

  • Lack of Supporting Documentation

    Insufficient documentation of diagnostic criteria for CFS, including symptom duration and severity, leading to audit denials and compliance issues.

Mitigation Tips

Best Practices
  • Document symptom duration, severity, onset for ME/CFS diagnosis coding.
  • ICD-10 G93.3: Ensure accurate Chronic Fatigue Syndrome coding compliance.
  • Rule out other conditions for accurate ME/CFS clinical documentation.
  • Assess functional limitations, energy levels for improved CDI of CFS.
  • Query physician for symptom details impacting daily activities for G93.3.

Clinical Decision Support

Checklist
  • 1. R/O other medical/psychiatric conditions (ICD-10 G93.3).
  • 2. Document substantial reduction in activity level.
  • 3. Post-exertional malaise (PEM) documented?
  • 4. Unrefreshing sleep noted in patient history?
  • 5. Cognitive impairment or orthostatic intolerance?

Reimbursement and Quality Metrics

Impact Summary
  • Chronic Fatigue (CFS, ME/CFS) reimbursement impacted by coding complexity, affecting medical billing revenue cycle.
  • ICD-10 coding accuracy crucial for Chronic Fatigue Syndrome claims. Optimize HCC coding for risk adjustment.
  • ME/CFS diagnosis impacts hospital reporting on patient outcomes, resource utilization, and quality metrics.
  • Proper coding of Chronic Fatigue improves data accuracy for population health management and value-based care.

Streamline Your Medical Coding

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Frequently Asked Questions

Common Questions and Answers

Q: What are the key diagnostic criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) according to the 2015 International Consensus Criteria?

A: The 2015 International Consensus Criteria for ME/CFS emphasizes post-exertional malaise (PEM) as a cardinal symptom. Diagnosis requires substantial reduction or impairment in the ability to engage in pre-illness levels of occupational, educational, social, or personal activities that persists for more than 6 months and is accompanied by fatigue that is not relieved by rest. In addition to PEM, at least one of the following three symptoms must be present: unrefreshing sleep, cognitive impairment (often described as "brain fog"), and orthostatic intolerance. Explore how these criteria can be systematically assessed in a clinical setting to differentiate ME/CFS from other conditions with similar symptoms like fibromyalgia or multiple sclerosis.

Q: How can clinicians differentiate between chronic fatigue and Chronic Fatigue Syndrome (CFS/ME) in patients presenting with persistent fatigue?

A: While fatigue is a common symptom in many conditions, Chronic Fatigue Syndrome, also known as Myalgic Encephalomyelitis (ME/CFS), presents with specific features that distinguish it from general chronic fatigue. The key differentiator is post-exertional malaise (PEM), a significant worsening of symptoms after even minor physical or cognitive exertion that can last for days or even weeks. Other characteristic features include unrefreshing sleep, cognitive dysfunction, and orthostatic intolerance. Clinicians should consider implementing a thorough patient history, including symptom duration and impact on daily activities, alongside physical examination and targeted diagnostic tests to rule out other medical or psychiatric conditions. Learn more about validated assessment tools, such as the DePaul Symptom Questionnaire, to aid in the diagnostic process.

Quick Tips

Practical Coding Tips
  • Code G93.3 for ME/CFS
  • Document symptom duration
  • Query physician for clarity
  • Review CDC guidelines for CFS
  • Check payer-specific coding rules

Documentation Templates

Patient presents with persistent, unexplained fatigue lasting more than six months, meeting the diagnostic criteria for Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME/CFS).  Symptoms reported include post-exertional malaise, unrefreshing sleep, cognitive impairment (brain fog), and orthostatic intolerance.  The onset of fatigue is not explained by other underlying medical conditions.  A comprehensive review of systems and physical examination were conducted, ruling out alternative diagnoses such as hypothyroidism, sleep disorders, and depression.  Laboratory tests including complete blood count (CBC), comprehensive metabolic panel (CMP), and thyroid stimulating hormone (TSH) were ordered and results are pending.  Differential diagnosis includes fibromyalgia, multiple sclerosis, and autoimmune disorders.  The patient's current functional status is significantly impacted by fatigue, limiting daily activities and work productivity.  Initial treatment plan focuses on symptom management, including graded exercise therapy, cognitive behavioral therapy (CBT), and medication management for pain and sleep disturbances.  Patient education on energy conservation and activity management strategies provided.  Follow-up appointment scheduled to review lab results, assess treatment response, and adjust management plan as needed.  ICD-10 code G93.3 (Chronic Fatigue Syndrome) is applied.  This documentation supports medical necessity for ongoing treatment and management of Chronic Fatigue.