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C54.1
ICD-10-CM
Endometrial Adenocarcinoma

Find comprehensive information on Endometrial Adenocarcinoma, also known as Uterine Cancer or Endometrial Cancer, including details on diagnosis, ICD-10 coding, clinical documentation requirements, treatment options, and healthcare resources. Learn about staging, prognosis, and best practices for medical coding related to Endometrial Adenocarcinoma for accurate clinical documentation and billing. This resource provides valuable insights for healthcare professionals, including physicians, nurses, and medical coders.

Also known as

Uterine Cancer
Endometrial Cancer

Diagnosis Snapshot

Key Facts
  • Definition : Cancerous tumor of the uterine lining (endometrium).
  • Clinical Signs : Abnormal vaginal bleeding, especially postmenopausal, pelvic pain, or watery discharge.
  • Common Settings : Gynecology clinic, oncology center, hospital.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC C54.1 Coding
C54.1

Malignant neoplasm of corpus uteri

Cancer specifically affecting the body of the uterus.

C54.0

Malignant neoplasm of isthmus uteri

Cancer affecting the narrow part of the uterus.

C55

Malignant neoplasm of cervix uteri

Cancer affecting the lower part of the uterus that opens into the vagina.

C79.89

Secondary malignant neoplasm of uterus

Cancer that has spread to the uterus from another site.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the endometrial adenocarcinoma specified as in situ?

  • Yes

    Code C54.11, Endometrial adenocarcinoma in situ

  • No

    Is there uterus involvement only?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Cancer of the uterine lining.
Precancerous changes in the uterine lining.
Precancerous glandular cells in the uterine lining.

Documentation Best Practices

Documentation Checklist
  • Endometrial adenocarcinoma diagnosis: Document laterality
  • Uterine cancer: Stage, grade (FIGO) required
  • Endometrial cancer: Histology confirmation needed
  • Document tumor size, myometrial invasion
  • Adenocarcinoma: Lymph node involvement status

Coding and Audit Risks

Common Risks
  • Laterality Coding

    Missing or incorrect laterality specification for endometrial adenocarcinoma impacts staging and treatment data accuracy.

  • Histology Specificity

    Unspecified histology (e.g., NOS) for endometrial adenocarcinoma may lead to inaccurate coding, affecting quality reporting.

  • Myometrial Invasion

    Accurate documentation of myometrial invasion depth is crucial for proper staging of endometrial cancer and impacts reimbursement.

Mitigation Tips

Best Practices
  • Complete endometrial sampling for accurate diagnosis ICD-10 C54
  • Document risk factors: obesity, estrogen therapy SNOMED CT 703684004
  • Stage precisely using FIGO staging, imaging, pathology ICD-O-3 8380/3
  • Assess for Lynch syndrome via genetic testing, family history LOINC 69889-6
  • Multidisciplinary team review for optimal treatment plan HCPCS G0283

Clinical Decision Support

Checklist
  • Verify abnormal uterine bleeding documented (ICD-10 N28.89)
  • Histopathology confirms endometrial adenocarcinoma (ICD-10 C54.9)
  • Assess for risk factors: obesity, nulliparity, tamoxifen (Estrogen Risk Documented)
  • Evaluate for Lynch Syndrome (Family History Assessed)
  • Pre-op imaging: consider pelvic ultrasound or MRI (Imaging Report)

Reimbursement and Quality Metrics

Impact Summary
  • Endometrial Adenocarcinoma (E) reimbursement hinges on accurate ICD-10-CM coding (C54.1, C54.2, etc.) and proper staging documentation for optimal MS-DRG assignment.
  • Coding quality directly impacts endometrial cancer case mix index (CMI) and hospital reimbursement. Accurate coding and abstracting are crucial.
  • Timely and specific documentation of uterine cancer treatment (surgery, chemo, radiation) influences hospital quality reporting metrics.
  • Accurate diagnosis coding for endometrial cancer (ICD-10 C54.-) is vital for cancer registry data, impacting future research and funding.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes for . Our AI-powered assistant ensures compliance and reduces coding errors.

Frequently Asked Questions

Common Questions and Answers

Q: What are the most effective current staging guidelines for endometrial adenocarcinoma to ensure accurate prognostication and treatment planning?

A: Accurate staging of endometrial adenocarcinoma is crucial for prognostication and personalized treatment planning. The current gold standard is the 2009 FIGO staging system, which incorporates surgical findings, including the depth of myometrial invasion, cervical stromal involvement, and the presence of extrauterine spread to adnexa, lymph nodes, and distant sites. This system helps clinicians stratify patients into distinct risk categories and guide treatment decisions, ranging from surgery alone for early-stage disease to adjuvant chemotherapy and radiation for advanced stages. Consider implementing a standardized staging protocol in your practice to ensure consistent and accurate application of the FIGO guidelines. Explore how molecular profiling can further refine risk stratification and personalize treatment strategies for endometrial adenocarcinoma.

Q: How can I differentiate between Type I and Type II endometrial adenocarcinoma in my clinical practice, considering their distinct molecular profiles and prognostic implications?

A: Distinguishing between Type I and Type II endometrial adenocarcinoma is essential for optimal patient management due to their differing molecular profiles and prognoses. Type I, often associated with estrogen excess, typically exhibits endometrioid histology, lower grade, and better prognosis. Type II, less common but more aggressive, often presents with serous or clear cell histology, higher grade, and tends to have deeper myometrial invasion and lymphatic spread. While histopathology remains the primary diagnostic tool, immunohistochemistry can be valuable in challenging cases. Explore how incorporating molecular markers, such as POLE mutations and p53 overexpression, can further enhance diagnostic accuracy and guide treatment selection for these distinct subtypes. Learn more about the evolving role of molecular classification in refining our understanding and management of endometrial adenocarcinoma.

Quick Tips

Practical Coding Tips
  • Code C54.1 for endometrial adenocarcinoma
  • Document tumor grade/stage for C54.1
  • Check laterality codes if applicable
  • Consider morphology codes, e.g., M8140/3
  • Abstract uterine cancer as C54.1

Documentation Templates

Patient presents with complaints consistent with possible endometrial adenocarcinoma, also known as uterine cancer or endometrial cancer.  Key symptoms include abnormal uterine bleeding, specifically postmenopausal bleeding or irregular periods, along with pelvic pain or pressure.  Differential diagnoses considered include endometrial hyperplasia, uterine fibroids, and other gynecologic malignancies.  Physical examination revealed normal external genitalia.  Bimanual exam revealed a slightly enlarged uterus.  Pelvic ultrasound was performed and demonstrated endometrial thickening, prompting endometrial biopsy for histopathological evaluation.  Biopsy results confirmed the diagnosis of endometrial adenocarcinoma, grade [Insert Grade].  Staging workup, including CT scan of the abdomen and pelvis, chest x-ray, and CA-125 levels, is planned to determine the extent of disease.  The patient was counseled regarding treatment options, including total hysterectomy with bilateral salpingo-oophorectomy, potentially followed by adjuvant radiation therapy or chemotherapy depending on final staging.  Risks and benefits of each treatment modality were discussed.  Patient understands the diagnosis and plan and will schedule a follow-up appointment to discuss surgical planning and answer any further questions.  The patient's medical history includes [relevant medical history such as hypertension, diabetes, obesity, or family history of cancer].  Current medications include [list current medications].  Allergies include [list any allergies].  ICD-10 code C54.1 is recorded for endometrial adenocarcinoma.  Further coding will be completed upon completion of staging and treatment.
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