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A49.8
ICD-10-CM
Gram-Positive Cocci Infections

Learn about Gram-positive cocci infections, including Streptococcus and Staphylococcus, clinical manifestations, diagnostic criteria, and appropriate medical coding for accurate healthcare documentation. This resource covers treatment options, microbiology lab tests, ICD-10 codes, and best practices for clinicians and healthcare professionals dealing with gram positive bacterial infections. Explore information on common infections like pneumonia, cellulitis, and bacteremia caused by gram-positive cocci.

Also known as

GPC Infections
Gram-Positive Bacterial Infections

Diagnosis Snapshot

Key Facts
  • Definition : Bacterial infections caused by spherical, Gram-positive organisms.
  • Clinical Signs : Vary widely depending on site of infection: skin infections, pneumonia, sepsis, toxic shock syndrome.
  • Common Settings : Community-acquired, hospital-acquired, healthcare-associated infections.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC A49.8 Coding
A49.0

Methicillin susceptible Staphylococcus aureus

Infection due to methicillin-susceptible S. aureus.

A49.1

Methicillin resistant Staphylococcus aureus

Infection due to methicillin-resistant S. aureus (MRSA).

B95.0-B95.8

Streptococcal infections

Infections caused by various types of streptococci.

A39

Meningococcal infection

Infection caused by Neisseria meningitidis bacteria.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the infection Methicillin-Resistant (MRSA)?

  • Yes

    Is it a skin infection?

  • No

    Is it Streptococcus pneumoniae?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Gram-Positive Cocci Infection
Staphylococcal Infection
Streptococcal Infection

Documentation Best Practices

Documentation Checklist
  • Document confirmed species (e.g., S. aureus)
  • Specify infection site (e.g., skin, lung)
  • Note specimen source (e.g., blood, wound)
  • Document Gram stain results
  • Record antibiotic susceptibility

Coding and Audit Risks

Common Risks
  • Unspecified Organism

    Coding Gram-Positive Cocci without specifying the organism (e.g., Staphylococcus, Streptococcus) leads to inaccurate data and DRG assignment.

  • Site and Severity Mixup

    Incorrect coding of infection site (e.g., skin vs. bloodstream) or severity (e.g., uncomplicated vs. sepsis) impacts reimbursement and quality metrics.

  • Missing Present on Admission

    Failing to document whether the infection was present on admission (POA) affects hospital-acquired infection reporting and payment.

Mitigation Tips

Best Practices
  • Ensure specific Gram stain, culture & sensitivity documentation for accurate ICD-10 coding (e.g., B95.8)
  • Document infection site, laterality, and clinical response for proper CPT coding and CDI
  • Validate antibiotic selection aligns with documented sensitivities for compliance and optimal patient care
  • Query physician for clarification on unspecified 'cocci' infections to improve coding specificity and reimbursement
  • Follow CLSI guidelines for specimen collection and processing to ensure reliable lab results for diagnosis

Clinical Decision Support

Checklist
  • Verify Gram stain: Positive cocci
  • Check morphology: Clusters, chains, pairs
  • Catalase test result documented
  • Consider patient risk factors: Age, comorbidities
  • Review culture/sensitivity for targeted antibiotics

Reimbursement and Quality Metrics

Impact Summary
  • Gram-Positive Cocci Infections Reimbursement: Accurate coding (ICD-10 A49, B95) impacts MS-DRG assignment and case mix index, affecting hospital payments. Coding audits and physician education improve compliance.
  • Quality Metrics Impact: Timely antibiotic administration, documented blood cultures, and infection control measures (NHSN reporting) influence hospital quality scores and value-based purchasing.
  • Coding Accuracy Impact: Specificity in coding (e.g., MRSA vs. MSSA) is crucial for accurate severity reflection, impacting reimbursement and public health surveillance.
  • Hospital Reporting Impact: Proper documentation and coding support accurate infection tracking, antibiotic stewardship programs, and hospital-acquired infection reporting.

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Frequently Asked Questions

Common Questions and Answers

Q: How can I differentiate between Staphylococcus aureus and Streptococcus pneumoniae gram-positive cocci infections in a clinical setting?

A: Differentiating between Staphylococcus aureus and Streptococcus pneumoniae, both gram-positive cocci, requires a multi-faceted approach. While both can cause respiratory infections, S. aureus often presents with skin and soft tissue infections like abscesses, while S. pneumoniae is more commonly associated with pneumonia and meningitis. Key distinguishing factors include: microscopic morphology (S. aureus appears in clusters, S. pneumoniae in pairs or chains), catalase test (S. aureus is positive, S. pneumoniae negative), and optochin susceptibility (S. pneumoniae is susceptible, S. aureus is resistant). Culture and sensitivity testing remain crucial for definitive identification and guiding antibiotic therapy. Consider implementing rapid diagnostic tests like PCR for faster identification, especially in critically ill patients. Explore how antibiotic stewardship principles can be applied when treating these infections.

Q: What are the recommended empiric antibiotic treatment options for suspected Methicillin-Resistant Staphylococcus aureus (MRSA) skin and soft tissue infection (SSTI) in adults?

A: Empiric antibiotic treatment for suspected MRSA skin and soft tissue infections in adults should consider local resistance patterns and patient-specific factors such as allergies and comorbidities. Commonly recommended options include vancomycin (IV), daptomycin (IV), linezolid (IV/PO), ceftaroline (IV), and tedizolid (IV/PO). For less severe infections, oral agents like doxycycline, trimethoprim-sulfamethoxazole (TMP-SMX), or clindamycin may be considered, though resistance patterns should be closely monitored. Culture and sensitivity testing are crucial for de-escalation to targeted therapy once results are available. Learn more about the importance of appropriate MRSA SSTI management to optimize patient outcomes and minimize resistance development.

Quick Tips

Practical Coding Tips
  • Code S. aureus MRSA B95.62
  • Document abscess site, depth
  • Strep pneumoniae, add J13
  • Enterococcus, code site, drug
  • Doc gram stain, culture results

Documentation Templates

Patient presents with signs and symptoms suggestive of a Gram-positive cocci infection.  Clinical presentation includes [specific symptoms e.g., fever, chills, localized pain, redness, swelling, purulent drainage, cough, shortness of breath, nausea, vomiting, headache, stiff neck, altered mental status].  Onset of symptoms occurred [timeframe].  Patient's medical history includes [relevant comorbidities e.g., diabetes, immunocompromise, recent surgery, indwelling medical devices].  Physical examination reveals [objective findings e.g., elevated temperature, tachycardia, tachypnea, hypotension, erythema, edema, tenderness, lymphadenopathy, abnormal lung sounds, meningeal signs].  Differential diagnosis includes [other possible infections e.g., other bacterial infections, viral infections, fungal infections].  Preliminary diagnosis of Gram-positive cocci infection is suspected based on clinical presentation and is pending confirmatory laboratory testing.  Ordered tests include [diagnostic tests e.g., Gram stain, culture and sensitivity, complete blood count, blood cultures, urinalysis, chest x-ray, lumbar puncture].  Initial treatment plan includes [empiric antibiotic therapy e.g.,  vancomycin, cefazolin, oxacillin, penicillin] pending culture results. Patient education provided regarding infection control measures, medication administration, potential side effects, and follow-up care.  Patient will be monitored closely for response to treatment and any complications.  ICD-10 code [appropriate code based on infection site and type e.g., A49.9 for unspecified staphylococcal infection, J15.21 for pneumonia due to Streptococcus pneumoniae] will be used for billing purposes.  CPT codes for diagnostic tests and procedures will be documented accordingly. Further evaluation and management will be based on culture results and clinical response.  Plan to reassess patient in [timeframe].