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E83.110
ICD-10-CM
Hereditary Hemochromatosis

Find comprehensive information on Hereditary Hemochromatosis diagnosis, including clinical documentation, medical coding (ICD-10-CM code E83.11), genetic testing, iron overload, and treatment options. Learn about symptoms, screening, phlebotomy, and patient management guidelines for healthcare professionals. Explore resources for accurate medical record keeping and compliant billing related to hemochromatosis.

Also known as

Genetic Hemochromatosis
HFE Hemochromatosis

Diagnosis Snapshot

Key Facts
  • Definition : Genetic disorder causing excess iron absorption and organ damage.
  • Clinical Signs : Fatigue, joint pain, abdominal pain, liver disease, diabetes, skin darkening.
  • Common Settings : Primary care, gastroenterology, hepatology, endocrinology clinics.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC E83.110 Coding
E83.1

Hereditary hemochromatosis

Genetic disorder causing excess iron absorption.

E83.0

Secondary hemochromatosis

Excess iron due to other conditions, not genetic.

D64.8

Other specified anemias

May include anemia related to iron overload.

K70-K77

Diseases of liver

Hemochromatosis can cause liver damage/disease.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the hemochromatosis hereditary/familial?

  • Yes

    Is it HFE-related?

  • No

    Do NOT code as hereditary hemochromatosis. Consider secondary hemochromatosis codes (e.g., E83.0).

Code Comparison

Related Codes Comparison

When to use each related code

Description
Iron overload from genetic mutation
Secondary iron overload
Severe iron overload presenting in utero or neonatally.

Documentation Best Practices

Documentation Checklist
  • Document iron overload symptoms (fatigue, joint pain)
  • Serum iron, transferrin saturation, ferritin levels
  • Genetic testing for HFE gene mutations (C282Y, H63D)
  • Liver biopsy with iron quantification if indicated
  • Family history of hemochromatosis documented

Mitigation Tips

Best Practices
  • ICD-10 E83.1, phlebotomy, CDI: iron overload monitoring
  • Genetic testing (HFE gene), document family history, risk assessment
  • Early diagnosis, compliance: limit iron-rich foods, avoid supplements
  • Monitor transferrin saturation, ferritin levels, liver function tests (LFTs)
  • Patient education: diet, alcohol limitation, HCC screening compliance

Clinical Decision Support

Checklist
  • Check serum iron, transferrin saturation, and ferritin levels.
  • Review family history for HH or iron overload.
  • Consider genetic testing for HFE gene mutations (C282Y/H63D).
  • Evaluate for iron overload symptoms (fatigue, joint pain).
  • Assess liver function tests for hepatic involvement.

Reimbursement and Quality Metrics

Impact Summary
  • Hereditary Hemochromatosis: Reimbursement and Quality Metrics Impact Summary
  • ICD-10-CM: E83.11 (primary), supporting codes for organ damage crucial for accurate reimbursement.
  • Coding accuracy impacts DRG assignment, influencing hospital reimbursement and case-mix index.
  • Iron overload monitoring (serum ferritin, transferrin saturation) tied to quality metrics and pay-for-performance programs.
  • Genetic testing (HFE gene) coding impacts molecular diagnostics billing and lab test utilization reporting.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes. Our AI-powered assistant ensures compliance and reduces coding errors.

Quick Tips

Practical Coding Tips
  • Code primary HH E83.1
  • Confirm diagnosis with iron studies
  • Document genetic testing results
  • Specify HH type (if known)
  • Consider secondary hemochromatosis codes

Documentation Templates

Patient presents with symptoms suggestive of hereditary hemochromatosis, including fatigue, joint pain, abdominal pain, and skin hyperpigmentation.  The patient reports a family history of iron overload, raising suspicion for HFE-related hereditary hemochromatosis.  Physical examination reveals hepatomegaly.  Laboratory findings show elevated serum iron, transferrin saturation, and ferritin levels.  Genetic testing for HFE gene mutations (C282Y and H63D) is ordered to confirm the diagnosis of hereditary hemochromatosis or rule out other causes of iron overload, such as secondary hemochromatosis.  Initial diagnostic evaluation includes liver function tests (LFTs) to assess for liver damage and potential complications like cirrhosis or hepatocellular carcinoma.  Based on the patient's transferrin saturation and ferritin levels, therapeutic phlebotomy is recommended as the primary treatment to reduce excess iron stores.  Patient education regarding dietary iron restriction and avoidance of iron supplements is provided.  Follow-up appointments are scheduled to monitor iron levels, liver function, and overall response to treatment, focusing on iron chelation therapy if phlebotomy is contraindicated.  Medical coding will utilize ICD-10-CM code E83.11 for hereditary hemochromatosis and relevant CPT codes for phlebotomy (e.g., 36430) and laboratory tests.  This diagnosis and treatment plan are consistent with current clinical practice guidelines for the management of hemochromatosis.