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D89.2
ICD-10-CM
Hypergammaglobulinemia

Understand hypergammaglobulinemia with comprehensive information on diagnosis, causes, symptoms, and treatment. This resource covers relevant healthcare, clinical documentation, and medical coding terms, including ICD-10 codes, SNOMED CT codes, and lab test interpretations for elevated immunoglobulin levels. Learn about gammopathies, monoclonal gammopathy, polyclonal gammopathy, serum protein electrophoresis, immunofixation, and the role of these tests in identifying and managing hypergammaglobulinemia. Explore the connection between hypergammaglobulinemia and conditions like infections, autoimmune diseases, and multiple myeloma. Find resources for healthcare professionals focusing on accurate clinical documentation and medical coding best practices for hypergammaglobulinemia.

Also known as

Polyclonal hypergammaglobulinemia
Waldenstrom's hypergammaglobulinemic purpura

Diagnosis Snapshot

Key Facts
  • Definition : High levels of gamma globulins (antibodies) in the blood.
  • Clinical Signs : Often asymptomatic. May include fatigue, infections, or enlarged lymph nodes.
  • Common Settings : Infections, autoimmune diseases, certain cancers, liver disease.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC D89.2 Coding
D89.0

Polyclonal hypergammaglobulinemia

Elevated levels of multiple immunoglobulins.

R77.1

Abnormal findings on immunoglobulin

Indicates irregular immunoglobulin levels.

C88.0

Waldenstrom macroglobulinemia

A type of cancer causing high IgM levels.

D83.2

Common variable immunodeficiency

Immune deficiency with variable antibody levels, sometimes high IgG.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the hypergammaglobulinemia monoclonal?

  • Yes

    Associated with a specific disease?

  • No

    Associated with a specific disease?

Code Comparison

Related Codes Comparison

When to use each related code

Description
High gamma globulin levels
Multiple myeloma
MGUS (Monoclonal gammopathy)

Documentation Best Practices

Documentation Checklist
  • Document specific type of hypergammaglobulinemia (e.g., monoclonal, polyclonal)
  • Quantify gamma globulin levels with units (e.g., IgG, IgA, IgM)
  • Specify method used for gamma globulin measurement
  • Document underlying cause if known (e.g., infection, autoimmune disease)
  • Correlate with clinical findings and other lab results

Coding and Audit Risks

Common Risks
  • Unspecified Etiology

    Coding hypergammaglobulinemia without specifying the underlying cause (e.g., infection, autoimmune) leads to inaccurate reporting and potential claim denials. CDI crucial for clarification.

  • Monoclonal vs. Polyclonal

    Distinguishing between monoclonal and polyclonal gammopathies is critical for accurate coding and treatment. Incorrect classification impacts risk adjustment and resource allocation.

  • Symptom Coding Pitfalls

    Coding symptoms associated with hypergammaglobulinemia (e.g., fatigue, weakness) instead of the underlying condition misrepresents severity and impacts quality metrics.

Mitigation Tips

Best Practices
  • Document specific cause (ICD-10-CM coding)
  • Quantify gamma globulin levels for accurate CDI
  • Correlate with clinical findings, avoid unspecific diagnosis
  • Review medication list for drug-induced causes (compliance)
  • Consider age-related variations for proper interpretation

Clinical Decision Support

Checklist
  • Review SPEP/IFE: Confirm elevated gamma globulins
  • Assess underlying cause: Infection, autoimmune, malignancy?
  • Correlate clinical findings: Fatigue, infections, lymphadenopathy?
  • Check quantitative immunoglobulins: Measure IgG, IgA, IgM
  • Consider bone marrow biopsy: If indicated by clinical picture

Reimbursement and Quality Metrics

Impact Summary
  • Hypergammaglobulinemia reimbursement hinges on accurate ICD-10 coding (D89.1) and supporting documentation for medical necessity.
  • Quality metrics impacted: Case Mix Index (CMI) may be affected depending on comorbid conditions and severity.
  • Coding accuracy crucial for proper DRG assignment and maximizing reimbursement. Avoid unspecified codes for optimal payment.
  • Hospital reporting: Accurate hypergammaglobulinemia diagnosis data impacts resource allocation and quality improvement initiatives.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes for . Our AI-powered assistant ensures compliance and reduces coding errors.

Quick Tips

Practical Coding Tips
  • Code underlying cause, not just hypergammaglobulinemia
  • Document specific immunoglobulin type (IgG, IgA, IgM)
  • Query physician if cause is unclear for accurate coding
  • Consider D89.0 for unspecified hypergammaglobulinemia
  • Review lab results for precise immunoglobulin levels

Documentation Templates

Patient presents with [signs and symptoms such as fatigue, recurrent infections, lymphadenopathy, hepatosplenomegaly, or other relevant findings].  Differential diagnosis includes infections, autoimmune diseases, and lymphoproliferative disorders.  Laboratory evaluation reveals elevated gamma globulins, specifically [mention specific immunoglobulin isotypes if known e.g., IgG, IgA, IgM] on serum protein electrophoresis.  Hypergammaglobulinemia is noted.  Further workup to determine the underlying etiology of the elevated gamma globulins is indicated.  This may include quantitative immunoglobulin levels, serum free light chains, autoimmune panels, bone marrow biopsy if clinically indicated, and infectious disease testing as appropriate.  Patient education provided on hypergammaglobulinemia causes, diagnosis, and treatment options.  Plan for follow-up to discuss results and determine appropriate management based on the underlying cause.  ICD-10 code [appropriate ICD-10 code, e.g., D89.1 for polyclonal hypergammaglobulinemia, or more specific code if etiology is known] is considered.  Medical billing and coding will reflect the complexity of the evaluation and management.
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