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R79.89
ICD-10-CM
Increased Ammonia Level

Understanding increased ammonia levels, hyperammonemia, and its clinical significance is crucial for accurate diagnosis and treatment. This resource provides information on ammonia blood test interpretation, normal ammonia levels, symptoms of high ammonia, and causes of elevated ammonia. Learn about relevant medical coding (ICD-10 codes for hyperammonemia), differential diagnosis considerations, and the role of liver function tests in evaluating ammonia levels. Explore the connection between hepatic encephalopathy and elevated ammonia, along with treatment options and management strategies for patients with hyperammonemia.

Also known as

Hyperammonemia
Elevated Ammonia

Diagnosis Snapshot

Key Facts
  • Definition : Elevated blood ammonia, often from impaired liver function.
  • Clinical Signs : Confusion, tremors, vomiting, sleepiness, can lead to coma.
  • Common Settings : Liver failure, hepatic encephalopathy, inherited metabolic disorders.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC R79.89 Coding
E72.2

Hyperammonemia

Elevated ammonia levels in the blood.

K72.9

Liver disease, unspecified

Liver problems that may cause elevated ammonia.

R79.89

Other abnormal findings

Includes elevated ammonia as an abnormal lab result.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the increased ammonia level due to a specific underlying condition?

  • Yes

    Is it due to liver disease?

  • No

    Is the patient receiving chemotherapy?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Increased Ammonia Level
Hepatic Encephalopathy
Urea Cycle Disorder

Documentation Best Practices

Documentation Checklist
  • Document specific symptoms (e.g., confusion, lethargy)
  • Record initial ammonia level (quantitative value with units)
  • Document any potential causes (e.g., liver disease, medication)
  • Note diagnostic tests performed (e.g., liver function tests)
  • Document treatment plan and patient response to treatment

Coding and Audit Risks

Common Risks
  • Unspecified etiology

    Coding ammonia level increase without documenting the underlying cause can lead to rejected claims and inaccurate data.

  • Liver disease link

    Failing to code associated liver disease when present with hyperammonemia can impact DRG assignment and reimbursement.

  • Transient vs. persistent

    Incorrectly coding transient elevations as chronic can skew quality metrics and patient risk stratification.

Mitigation Tips

Best Practices
  • Document etiology: liver disease, meds, etc. (ICD-10-CM E72.2)
  • Precise ammonia level units (mcg/dL or umol/L) for accurate CDI
  • R/O hepatic encephalopathy: assess mental status, asterixis (ICD-10-CM K72.00)
  • Lactulose/rifaximin orders? Document indication, monitor response for compliance
  • Nutrition consult: restrict protein if indicated, monitor labs for improvement

Clinical Decision Support

Checklist
  • Verify elevated ammonia lab result: document units, method.
  • R/O lab error: redraw, check sample handling.
  • Assess hepatic function: LFTs, bilirubin, INR.
  • Consider inherited metabolic disorder if neonate/infant.
  • Document relevant medications: valproate, chemotherapies.

Reimbursement and Quality Metrics

Impact Summary
  • Reimbursement: Accurate coding of hyperammonemia (ICD-10 E72.2) crucial for appropriate reimbursement. Coding errors can lead to claim denials, impacting revenue cycle management.
  • Quality Metrics: Elevated ammonia levels impact patient safety indicators related to hepatic encephalopathy, requiring timely diagnosis and management for optimal outcomes.
  • Coding Accuracy: Specifying cause of hyperammonemia (e.g., liver failure, urea cycle disorders) improves coding specificity, impacting severity scores & case mix index.
  • Hospital Reporting: Precise documentation of ammonia levels and related conditions improves data quality for hospital reporting, impacting quality metrics and performance.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes for . Our AI-powered assistant ensures compliance and reduces coding errors.

Quick Tips

Practical Coding Tips
  • Code underlying liver disease
  • Document symptoms, e.g., confusion
  • Check for medication triggers
  • R72.8 for unspecified hyperammonemia
  • Consider transient causes in infants

Documentation Templates

Patient presents with signs and symptoms suggestive of hyperammonemia.  Clinical presentation includes (list presenting symptoms e.g., altered mental status, confusion, lethargy, vomiting, asterixis, seizures).  Initial evaluation reveals elevated ammonia levels (document specific level).  Differential diagnosis includes hepatic encephalopathy, urea cycle disorders, Reye's syndrome, inherited metabolic disorders, and drug-induced hyperammonemia.  Pertinent medical history includes (list relevant medical history e.g., liver disease, cirrhosis, hepatitis, use of valproic acid).  Family history is notable for (document any relevant family history of metabolic disorders).  Physical examination findings include (document relevant physical findings e.g., jaundice, ascites, hepatomegaly).  Laboratory testing includes ammonia level (document value and units), liver function tests (LFTs), complete blood count (CBC), basic metabolic panel (BMP), and coagulation studies.  Imaging studies (e.g., abdominal ultrasound, CT scan) may be considered to further evaluate the underlying cause.  Diagnosis of increased ammonia level is based on elevated serum ammonia concentration in conjunction with clinical presentation.  Treatment plan includes addressing the underlying cause of hyperammonemia and managing symptoms.  Specific treatments may include lactulose, rifaximin, protein restriction, intravenous fluids, and hemodialysis or other extracorporeal therapies in severe cases.  Patient education provided on dietary modifications, medication management, and the importance of follow-up care.  Prognosis depends on the underlying etiology and severity of the hyperammonemia.  Follow-up appointments are scheduled to monitor ammonia levels, assess treatment response, and adjust management as needed.  ICD-10 code E72.2 (disorders of ammonia metabolism) is appropriate for billing and coding purposes.
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