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D72.819
ICD-10-CM
Low White Blood Cell Count

Understanding low white blood cell count leukopenia neutropenia diagnosis and treatment is crucial for healthcare professionals. This resource provides information on WBC count differential clinical documentation ICD-10 codes for leukopenia neutropenia and related conditions like agranulocytosis and pancytopenia. Learn about symptoms causes and management of low white blood cells including bone marrow disorders chemotherapy side effects and immune deficiencies. Improve your clinical documentation and medical coding accuracy with this comprehensive guide to low white blood cell count.

Also known as

Leukopenia
Low WBC Count
neutropenia
+1 more

Diagnosis Snapshot

Key Facts
  • Definition : A decreased number of white blood cells (leukocytes) in the blood.
  • Clinical Signs : Frequent infections, fever, chills, weakness, fatigue, mouth sores.
  • Common Settings : Cancer treatment, autoimmune disorders, bone marrow disorders, infections.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC D72.819 Coding
D70-D72

Diseases of white blood cells

Covers various white blood cell disorders, including low counts.

D61

Aplastic and other anemias

Includes conditions where low white blood cells are a feature, like aplastic anemia.

R70-R79

Abnormal findings of blood

May be used for unspecified low white blood cell counts found in lab tests.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the low WBC due to chemotherapy, radiation, or other external agent?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Low White Blood Cell Count
Neutropenia
Lymphopenia

Documentation Best Practices

Documentation Checklist
  • Leukopenia diagnosis: Document WBC count below reference range.
  • Specify leukopenia type (neutropenia, lymphopenia, etc.).
  • Document symptom onset, duration, and severity.
  • Include relevant medical history, medications, and family history.
  • Document diagnostic tests performed (CBC with differential).

Coding and Audit Risks

Common Risks
  • Unspecified Leukopenia

    Coding leukopenia without specificity (e.g., D70.9) when clinical documentation supports a more specific type (e.g., neutropenia, lymphopenia).

  • Missed Causative Diagnosis

    Failing to code the underlying cause of the low WBC (e.g., chemotherapy, infection, autoimmune disease) impacts risk adjustment and quality metrics.

  • Unvalidated Low WBC

    Coding low WBC based on a single, unconfirmed lab result without clinical validation or follow-up investigation.

Mitigation Tips

Best Practices
  • Document cause of leukopenia: ICD-10-CM D72, improve CDI
  • Review meds, chemo, infection: SNOMED CT 301313004
  • Growth factors if severe neutropenia: ensure compliant Rx
  • Hygiene, infection control paramount: reduce risk, track in EHR
  • Monitor CBC, differentials regularly: optimize clinical coding

Clinical Decision Support

Checklist
  • Verify low WBC value: Document absolute neutrophil count.
  • Review medications: Rule out drug-induced neutropenia.
  • Assess for infection signs: Fever, chills, or localized symptoms.
  • Consider underlying conditions: Bone marrow disorders, autoimmune disease.

Reimbursement and Quality Metrics

Impact Summary
  • Low White Blood Cell Count reimbursement impacted by accurate ICD-10 coding (D70.*, R70.89) for optimal payment.
  • Leukopenia coding accuracy directly affects hospital MS-DRG assignment and case-mix index reporting.
  • Quality metrics for neutropenia, agranulocytosis, and pancytopenia rely on correct low WBC diagnosis coding.
  • Timely and specific leukopenia documentation improves severity level assignment for proper reimbursement.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes. Our AI-powered assistant ensures compliance and reduces coding errors.

Quick Tips

Practical Coding Tips
  • Code underlying cause, not just leukopenia
  • Specify WBC type (neutrophils, lymphocytes)
  • Document severity and symptoms
  • Consider D61.8 or related ICD-10 codes

Documentation Templates

Patient presents with leukopenia, characterized by a low white blood cell count (WBC) below the normal reference range.  Symptoms include fatigue, weakness, fever, chills, and increased susceptibility to infections.  Differential diagnosis considers neutropenia, lymphocytopenia, and other cytopenias.  Complete blood count (CBC) with differential, peripheral blood smear review, and comprehensive metabolic panel (CMP) were ordered to assess the severity and identify potential underlying etiologies such as viral infections, autoimmune disorders, bone marrow suppression, or medication-induced leukopenia.  Patient history includes recent chemotherapy treatment, which may be contributing to the current low WBC.  Assessment reveals an absolute neutrophil count (ANC) below the critical threshold, increasing the risk of serious infections.  Plan includes close monitoring of WBC and ANC, prophylactic antibiotics to mitigate infection risk, and patient education on infection prevention measures.  Further investigations may be warranted depending on the clinical course and response to initial management.  Medical coding will utilize appropriate ICD-10 codes for leukopenia and any identified underlying causes. Billing will reflect evaluation and management (E/M) services, laboratory tests, and prescribed medications.  Follow-up scheduled to reassess WBC count and adjust treatment plan as necessary.