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R59.9
ICD-10-CM
Lymphadenopathy

Understanding lymphadenopathy diagnosis, documentation, and medical coding is crucial for healthcare professionals. This resource provides information on enlarged or swollen lymph nodes, including differential diagnoses, ICD-10 codes (e.g., R59.1), SNOMED CT concepts, clinical findings, and appropriate documentation for accurate billing and coding. Learn about localized, generalized, and persistent lymphadenopathy, along with associated symptoms and diagnostic tests. Improve your clinical documentation and medical coding accuracy for lymphadenopathy.

Also known as

Swollen Lymph Nodes
Lymph Node Enlargement

Diagnosis Snapshot

Key Facts
  • Definition : Swollen lymph nodes, usually due to infection, but can also be caused by other conditions.
  • Clinical Signs : Enlarged, tender, sometimes firm or rubbery lymph nodes in the neck, armpits, groin, or other areas.
  • Common Settings : Primary care, urgent care, sometimes oncology or hematology depending on cause.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC R59.9 Coding
R59

Enlarged lymph nodes

Covers generalized lymphadenopathy and localized lymph node enlargement.

I88

Nonspecific lymphadenitis

Inflammation of lymph nodes, not classified elsewhere.

C77

Secondary and unspecified malignant neoplasm of lymph nodes

Malignant neoplasms that have spread to lymph nodes.

R16

Hepatomegaly and splenomegaly

May be associated with lymphadenopathy in some conditions.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is lymphadenopathy localized?

  • Yes

    Related to infection?

  • No

    Generalized lymphadenopathy?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Swollen lymph nodes
Localized lymphadenopathy
Generalized lymphadenopathy

Documentation Best Practices

Documentation Checklist
  • Lymphadenopathy location (e.g., cervical, axillary)
  • Lymphadenopathy size (cm)
  • Lymphadenopathy texture (e.g., soft, firm, mobile, fixed)
  • Associated symptoms (e.g., fever, night sweats, weight loss)
  • Relevant history (e.g., infection, malignancy)

Coding and Audit Risks

Common Risks
  • Unspecified Location

    Coding lymphadenopathy without specifying the affected site (e.g., cervical, axillary) leads to inaccurate coding and potential claim denials.

  • Generalized vs. Localized

    Misclassifying generalized lymphadenopathy as localized, or vice versa, impacts severity documentation and DRG assignment.

  • Underlying Cause Missing

    Failing to document the underlying etiology (e.g., infection, malignancy) hinders accurate coding and quality reporting.

Mitigation Tips

Best Practices
  • Document location, size, consistency for ICD-10 specificity (R59.x)
  • Detailed H&P crucial for accurate lymphadenopathy diagnosis coding.
  • Correlate labs, imaging with clinical findings for CDI compliance.
  • Rule out infections, malignancies for proper HCC coding & billing.
  • Consider biopsy for definitive diagnosis, improving CDI accuracy.

Clinical Decision Support

Checklist
  • Confirm enlarged lymph node: Location, size, consistency (ICD-10 R59.*, I88.9)
  • Patient age, symptoms onset, duration, associated symptoms documented (SNOMED CT)
  • Assess for infection, inflammation, malignancy: CBC, imaging (CPT codes)
  • Review medication history: Drug-induced lymphadenopathy? (RxNorm)
  • Biopsy if indicated: Histopathology for definitive diagnosis (ICD-10, SNOMED CT)

Reimbursement and Quality Metrics

Impact Summary
  • Lymphadenopathy reimbursement hinges on accurate ICD-10 coding (e.g., R59.1, underlying cause) for optimal payer specificity.
  • Quality metrics for lymphadenopathy may involve time to diagnosis, treatment initiation, and patient-reported outcomes.
  • Precise documentation linking lymphadenopathy to infection, malignancy or other etiology impacts severity level and coding.
  • Case management and appropriate follow-up care influence lymphadenopathy reimbursement and patient outcomes reporting.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes. Our AI-powered assistant ensures compliance and reduces coding errors.

Quick Tips

Practical Coding Tips
  • Code specific site, laterality
  • Document size, consistency
  • Specify generalized vs localized
  • Consider underlying etiology code
  • Rule out lymphadenitis

Documentation Templates

Patient presents with lymphadenopathy, characterized by enlarged lymph nodes.  Assessment includes location, size, consistency, mobility, tenderness, and associated symptoms.  Differential diagnosis considers infectious causes such as mononucleosis, streptococcal pharyngitis, tuberculosis, cat scratch disease, and HIV, as well as non-infectious etiologies including lymphoma, leukemia, autoimmune disorders like lupus and rheumatoid arthritis, and medications.  Physical examination reveals palpable lymph nodes in the [specify location e.g., cervical, axillary, inguinal] region, measuring [size in cm].  Nodes are [consistency e.g., firm, rubbery, soft], [mobility e.g., mobile, fixed], and [tenderness e.g., tender, non-tender].  Patient reports [associated symptoms e.g., fever, fatigue, night sweats, weight loss, sore throat, upper respiratory infection symptoms].  Diagnostic workup may include complete blood count (CBC) with differential, peripheral blood smear, lymph node biopsy, imaging studies such as ultrasound or CT scan, and serological testing for infectious agents depending on clinical suspicion.  Treatment plan is dependent on the underlying cause of the lymphadenopathy and may include antibiotics for bacterial infections, antiviral medications for viral infections, observation for reactive lymphadenopathy, or referral to a hematologist or oncologist for suspected malignancy.  Patient education provided regarding the diagnosis, potential causes, treatment options, and follow-up care.  ICD-10 code R59.1 (localized lymphadenopathy) or R59.8 (other specified lymphadenopathy) may be appropriate depending on the specific presentation, with further specification if the underlying cause is identified.  CPT codes for procedures performed, such as a lymph node biopsy (e.g., 38500-38525), should be documented accordingly.
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