Facebook tracking pixel
D72.825
ICD-10-CM
Monocytosis

Understand monocytosis diagnosis, elevated monocyte count, causes, and symptoms. Learn about monocyte blood test interpretation, differential diagnosis considerations, and related conditions like mononucleosis. Explore ICD-10 codes for monocytosis, clinical documentation best practices, and healthcare implications of increased monocytes. Find information on monocytosis treatment and management strategies for patients and healthcare professionals.

Also known as

Elevated Monocytes
Symptomatic Monocytosis

Diagnosis Snapshot

Key Facts
  • Definition : Increased monocytes in the blood, often indicating infection or inflammation.
  • Clinical Signs : May be asymptomatic, or present with fatigue, fever, or symptoms related to the underlying cause.
  • Common Settings : Infections (viral, bacterial, parasitic), autoimmune diseases, some cancers.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC D72.825 Coding
D72.82

Other specified monocytosis

This code signifies an increase in monocytes without a specified cause.

R78.89

Other abnormal findings of blood cell morphology

Includes various blood cell abnormalities, sometimes encompassing monocytosis.

D72.0

Genetic anomalies of leukocytes

Some genetic conditions can cause elevated monocyte levels.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is monocytosis due to a documented underlying condition?

  • Yes

    Is it due to malignancy?

  • No

    Code D72.820 Monocytosis, unspecified.

Code Comparison

Related Codes Comparison

When to use each related code

Description
Increased monocytes in blood.
Chronic myelomonocytic leukemia
Reactive monocytosis

Documentation Best Practices

Documentation Checklist
  • Monocytosis diagnosis documented
  • Underlying cause of monocytosis noted
  • Complete blood count (CBC) with differential
  • Peripheral blood smear review findings
  • Correlation with clinical symptoms & signs

Coding and Audit Risks

Common Risks
  • Unspecified Monocytosis

    Coding monocytosis without specifying reactive, transient, or other causes leads to inaccurate data and potential underpayment. Affects CDI, HCC coding.

  • Missed Secondary Monocytosis

    Failing to code the underlying condition causing monocytosis (e.g., infection, malignancy) impacts risk adjustment and quality metrics. CDI, coder focus.

  • Monocytosis Clinical Validation

    Lack of proper clinical documentation supporting monocytosis diagnosis can trigger audit denials and compliance issues. CDI, physician documentation.

Mitigation Tips

Best Practices
  • Document underlying cause per ICD-10 guidelines for monocytosis coding.
  • Ensure CDI of infection, inflammation, or malignancy for accurate reimbursement.
  • Review blood smear morphology for compliance with diagnostic criteria.
  • Monitor patient for disease progression and document treatment response for HCC.
  • Correlate monocytosis with clinical findings to avoid medical necessity denials.

Clinical Decision Support

Checklist
  • Review CBC: Verify absolute monocyte count >1.0 x 10^9/L
  • Correlate with clinical context: Infection, inflammation, malignancy?
  • Review peripheral smear: Confirm monocyte morphology
  • Consider underlying causes: Document etiology if known
  • Exclude reactive monocytosis: Assess for infection resolution

Reimbursement and Quality Metrics

Impact Summary
  • Monocytosis coding accuracy impacts reimbursement for CBC and differentials.
  • Proper ICD-10 coding (e.g., D72.82) for monocytosis affects hospital case mix index.
  • Monocytosis documentation specificity improves quality reporting for infection control.
  • Accurate monocytosis reporting impacts severity scores and resource utilization metrics.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes for . Our AI-powered assistant ensures compliance and reduces coding errors.

Quick Tips

Practical Coding Tips
  • Code monocytosis D72.8
  • Document reactive vs. neoplastic
  • Specify underlying cause if known
  • Consider morphology, count
  • Check clinical findings for clues

Documentation Templates

Patient presents with elevated monocyte count, consistent with monocytosis.  Differential diagnosis includes infection (bacterial, viral, fungal, parasitic), chronic inflammation (inflammatory bowel disease, rheumatoid arthritis), hematologic malignancy (chronic myelomonocytic leukemia, acute myeloid leukemia), granulomatous disease (sarcoidosis, tuberculosis), autoimmune disorders (systemic lupus erythematosus), and recovery from bone marrow suppression.  Complete blood count with differential demonstrates absolute monocyte count above the normal range.  Patient's symptoms include fatigue, malaise, and low-grade fever.  Physical examination findings are unremarkable except for mild splenomegaly.  Further investigations to determine the underlying etiology of monocytosis may include peripheral blood smear review, bone marrow biopsy, infectious disease workup (blood cultures, serologies), imaging studies (chest X-ray, CT scan), and autoimmune panels.  Treatment plan is directed at managing the underlying cause of the elevated monocytes.  Patient education provided regarding monocyte function, potential causes of monocytosis, and the importance of follow-up care.  ICD-10 code D72.821, Other specified disorders involving monocytes.  CPT codes for relevant laboratory and diagnostic procedures will be documented separately.  Follow-up scheduled to reassess monocyte levels and further evaluate potential underlying conditions.
Monocytosis - AI-Powered ICD-10 Documentation