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A41.02
ICD-10-CM
MRSA Sepsis

Learn about MRSA sepsis diagnosis, including clinical documentation requirements, ICD-10 codes (A41.01, A41.9), and common symptoms like fever, chills, and hypotension. This guide covers best practices for healthcare professionals regarding MRSA bacteremia, septicemia, and blood culture interpretation for accurate medical coding and improved patient care. Explore resources for sepsis treatment guidelines, risk factors, and the importance of timely diagnosis in managing methicillin-resistant Staphylococcus aureus infections.

Also known as

Methicillin-resistant Staphylococcus aureus sepsis
MRSA bloodstream infection

Diagnosis Snapshot

Key Facts
  • Definition : Severe infection caused by methicillin-resistant Staphylococcus aureus bacteria.
  • Clinical Signs : Fever, chills, rapid heart rate, low blood pressure, skin infection, and altered mental status.
  • Common Settings : Hospitals, nursing homes, and other healthcare facilities; also community-acquired.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC A41.02 Coding
A41.01

Sepsis due to Methicillin-resistant S. aureus

Sepsis specifically caused by MRSA bacteria.

A41.9

Sepsis, unspecified organism

Sepsis where the causative organism is unknown.

R65.21

Severe sepsis with septic shock

Advanced, life-threatening stage of sepsis with shock.

J15.212

Pneumonia due to MRSA

Lung infection by MRSA, a potential source of sepsis.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the MRSA infection systemic?

  • Yes

    Is there organ dysfunction?

  • No

    Is the site of infection known?

Code Comparison

Related Codes Comparison

When to use each related code

Description
MRSA sepsis
Staph aureus sepsis
Severe sepsis

Documentation Best Practices

Documentation Checklist
  • MRSA sepsis diagnosis documentation: blood culture positive for MRSA
  • Document systemic inflammatory response syndrome (SIRS) criteria
  • Specify organ dysfunction due to sepsis
  • Document source of MRSA infection if known
  • ICD-10-CM code A41.01 for MRSA sepsis

Coding and Audit Risks

Common Risks
  • Sepsis Documentation

    Insufficient documentation linking MRSA to sepsis, potentially leading to incorrect coding without explicit clinical indicators.

  • Unspecified MRSA Site

    Coding MRSA sepsis without specifying the infection source (e.g., pneumonia, bacteremia) can result in coding errors and claims denials.

  • SIRS vs. Sepsis

    Misdiagnosis of systemic inflammatory response syndrome (SIRS) as sepsis with MRSA can lead to upcoding and compliance issues.

Mitigation Tips

Best Practices
  • Document site of infection for accurate coding (ICD-10-CM)
  • Blood cultures essential: CDI of MRSA sepsis requires positive result
  • Timely antibiotics crucial: Document start time for compliance
  • Query MD for clarity if documentation lacks sepsis specificity
  • Review labs/vitals: CDI for SOFA score supports sepsis severity

Clinical Decision Support

Checklist
  • Suspected infection source identified and documented (ICD-10)
  • Positive MRSA culture or PCR (LOINC, SNOMED CT)
  • SIRS criteria met plus documented organ dysfunction (Sepsis-3)
  • Appropriate antibiotics ordered (RxNorm, patient safety)
  • Repeat cultures after 24-48hrs of antibiotics (infection control)

Reimbursement and Quality Metrics

Impact Summary
  • MRSA Sepsis reimbursement hinges on accurate ICD-10-CM coding (A41.01, other codes) and present on admission indicator.
  • Sepsis quality metrics: Sep-1 timely antibiotics, lactate measurement impact hospital value-based purchasing.
  • Coding errors for MRSA Sepsis delay claims, reduce reimbursement, negatively affecting revenue cycle management.
  • Accurate documentation of infection site, severity markers improves sepsis severity level for optimal reimbursement.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes for . Our AI-powered assistant ensures compliance and reduces coding errors.

Quick Tips

Practical Coding Tips
  • Code MRSA sepsis A41.01
  • Document positive blood culture
  • Query physician if MRSA unspecified
  • Code SIRS if present R65.10
  • Code organ dysfunction if septic shock

Documentation Templates

Patient presents with suspected Methicillin-resistant Staphylococcus aureus (MRSA) sepsis.  Clinical manifestations include fever (temperature 102.5 F), chills, tachycardia (heart rate 110 bpm), tachypnea (respiratory rate 24 breaths per minute), and hypotension (blood pressure 9060 mmHg).  The patient reports malaise, body aches, and decreased urine output.  Leukocytosis is noted on complete blood count (CBC) with a white blood cell (WBC) count of 18,000 cellsmm3 and elevated procalcitonin.  Blood cultures have been drawn and sent for analysis to confirm MRSA bacteremia.  Given the patient's clinical picture concerning for severe sepsis secondary to suspected MRSA infection,  broad-spectrum intravenous antibiotics (Vancomycin) have been initiated.  Fluid resuscitation with normal saline is underway to address hypotension and improve tissue perfusion.  The patient is being closely monitored for signs of septic shock and organ dysfunction.  Differential diagnosis includes other bacterial infections, viral sepsis, and non-infectious causes of systemic inflammatory response syndrome (SIRS).  Further diagnostic testing, including lactate levels and possible imaging studies (chest x-ray, CT scan), may be warranted depending on clinical course and response to initial therapy.  ICD-10 code A41.02 (Sepsis due to Methicillin-resistant Staphylococcus aureus) is being considered pending blood culture confirmation.  Treatment plan includes continued hemodynamic support, antibiotic therapy tailored to culture sensitivities, and supportive care as indicated.  Patient's condition and response to treatment will be reassessed frequently.