Find comprehensive information on Myeloproliferative Neoplasms MPN including clinical documentation requirements, ICD-10-CM diagnosis codes, medical coding guidelines, and healthcare resources for Essential Thrombocythemia ET, Polycythemia Vera PV, and Myelofibrosis MF. Learn about symptom management, treatment options, and prognosis for Myeloproliferative Disorders MPD. This resource provides valuable insights for healthcare professionals, coders, and patients seeking information on Myeloproliferative diseases.
Also known as
Chronic myeloproliferative disorders
Group of disorders where bone marrow makes too many blood cells.
Myeloid and lymphoid neoplasms
Cancers affecting bone marrow and lymphatic system, sometimes overlapping.
Other disorders of blood and blood-forming organs
Catch-all for blood disorders not classified elsewhere, may include rare myeloproliferative diseases.
Follow this step-by-step guide to choose the correct ICD-10 code.
Is the myeloproliferative disorder chronic myeloid leukemia (CML)?
Yes
Code C92.1 for CML, chronic phase; C92.0 for CML, accelerated phase; C92.10 for CML, unspecified; C92.a1 for CML, blast crisis; C92.a2 for CML in remission
No
Is it Polycythemia Vera?
When to use each related code
Description |
---|
Overproduction of blood cells |
Chronic blood cancer, high platelets |
Bone marrow fibrosis, enlarged spleen |
Coding MDS without specifying subtype (e.g., using D47.9 instead of D47.1) leads to inaccurate DRG assignment and reimbursement.
Misdiagnosis between MPN (D47.1) and MDS (D46.-) due to similar symptoms can impact quality metrics and treatment plans.
Failure to document JAK2 mutation status (positive/negative) for MPN affects risk stratification and treatment selection, impacting coding accuracy.
Patient presents with symptoms suggestive of a myeloproliferative neoplasm (MPN). Key findings include [Specify symptoms e.g., splenomegaly, fatigue, night sweats, weight loss, pruritus, bone pain, early satiety, abdominal fullness]. Complete blood count (CBC) reveals [Specify CBC findings e.g., elevated white blood cell count, elevated red blood cell count, elevated platelet count, presence of immature myeloid cells]. Peripheral blood smear shows [Specify findings e.g., anisopoikilocytosis, teardrop cells, nucleated red blood cells, left shift]. Bone marrow biopsy results indicate [Specify findings e.g., hypercellularity, increased megakaryocytes, reticulin fibrosis, JAK2 V617F mutation status]. Based on these findings, the diagnosis of myeloproliferative disorder is suspected, with a differential diagnosis including polycythemia vera, essential thrombocythemia, primary myelofibrosis, and chronic myeloid leukemia. Further evaluation, including molecular testing for JAK2, CALR, and MPL mutations, is being performed to confirm the specific MPN subtype and guide treatment decisions. Patient education regarding the nature of MPN, prognosis, and treatment options was provided. Treatment plan will be determined based on the specific MPN subtype, disease risk stratification, and patient symptoms. Potential treatment options include phlebotomy, low-dose aspirin, hydroxyurea, JAK2 inhibitors (e.g., ruxolitinib), and allogeneic stem cell transplantation. Regular monitoring of blood counts, disease symptoms, and potential treatment complications will be essential. ICD-10 code [Specify relevant ICD-10 code, e.g., D47.1] is being considered pending confirmatory testing. Medical billing codes for evaluation and management, laboratory testing, and procedures performed will be documented accordingly.