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C48.2
ICD-10-CM
Peritoneal Cancer

Find comprehensive information on peritoneal cancer, including diagnosis codes (ICD-10 C48, C78), clinical documentation requirements, and healthcare resources. Learn about peritoneal carcinomatosis, primary peritoneal cancer, and related medical coding guidelines for accurate billing and reimbursement. Explore treatment options, prognosis, and support services for patients diagnosed with peritoneal cancer. This resource offers valuable insights for healthcare professionals, coders, and patients seeking information on this rare malignancy.

Also known as

Peritoneal Carcinomatosis
Carcinoma of Peritoneum
Primary Peritoneal Cancer

Diagnosis Snapshot

Key Facts
  • Definition : Cancer in the peritoneum (lining of abdomen), often from other cancers spreading.
  • Clinical Signs : Abdominal swelling, pain, fluid buildup (ascites), weight loss, bowel changes.
  • Common Settings : Oncology clinics, hospitals, surgical centers, palliative care.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC C48.2 Coding
C48.1

Peritoneal mesothelioma

Cancer specifically affecting the peritoneum lining.

C78.6

Peritoneal carcinomatosis

Cancer that has spread to the peritoneum from another site.

C48.0

Retroperitoneal mesothelioma

Cancer affecting the tissues behind the peritoneum.

C15-C26

Malignant neoplasms digestive organs

Cancers of digestive organs that may spread to peritoneum.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the peritoneal cancer primary?

  • Yes

    Specify the primary site.

  • No

    Is the primary site known?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Peritoneal Cancer
Peritoneal Metastasis
Primary Peritoneal Serous Carcinoma

Documentation Best Practices

Documentation Checklist
  • Peritoneal Cancer ICD-10 C48, C78.6 documentation: site, histology
  • Malignant ascites, peritoneal carcinomatosis: cytology report
  • PC staging: TNM, primary site, mets documented
  • Surgical exploration findings: tumor size, location, spread
  • Treatment plan: chemo, surgery, palliative care specified

Coding and Audit Risks

Common Risks
  • Primary Site Miscoding

    Incorrect coding of the primary site of peritoneal cancer, often confused with ovarian or other abdominal cancers, impacting accurate staging and treatment.

  • Histology Specificity

    Lack of specific histology documentation may lead to generic coding of peritoneal cancer, affecting treatment planning and research data accuracy.

  • Malignant Ascites Coding

    Confusion in coding malignant ascites as a separate diagnosis or part of peritoneal cancer may lead to inflated comorbidity scores and inaccurate resource allocation.

Mitigation Tips

Best Practices
  • Precise ICD-10 coding (C48, C78) for primary/secondary peritoneal cancer.
  • Detailed documentation of tumor location, size, and stage for accurate CDI.
  • Consistent pathology reports with clear histology for compliance and coding.
  • Regular physician queries for clarification improve CDI and risk adjustment.
  • Thorough documentation of treatment plans (surgery, chemo) supports correct coding.

Clinical Decision Support

Checklist
  • Review imaging (CT/MRI) for peritoneal thickening/nodularity: ICD-10 C78.6
  • Ascites analysis for malignant cells: ICD-10 R18.0, SNOMED CT 70909005
  • Laparoscopy/biopsy for tissue diagnosis confirmation: ICD-10 C48.1
  • Evaluate CA-125 levels: SNOMED CT 302393009, improve documentation specificity

Reimbursement and Quality Metrics

Impact Summary
  • Peritoneal Cancer Reimbursement: ICD-10 C48, C78.6 impacts DRG assignment, affecting hospital payments.
  • Coding Accuracy: Precise documentation of primary site, histology, stage (TNM) crucial for optimal reimbursement.
  • Quality Metrics: Peritoneal cancer survival rates, treatment complications influence hospital quality reporting.
  • Hospital Reporting: Accurate coding of peritoneal cancer diagnoses impacts cancer registry data, case mix index.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes for . Our AI-powered assistant ensures compliance and reduces coding errors.

Frequently Asked Questions

Common Questions and Answers

Q: What are the most effective current treatment strategies for managing malignant peritoneal mesothelioma in patients with unresectable disease?

A: For patients with unresectable malignant peritoneal mesothelioma, current treatment strategies often involve a multimodal approach. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) has demonstrated improved survival rates compared to systemic chemotherapy alone in select patient populations. Systemic chemotherapy regimens, typically including platinum-based agents like cisplatin or carboplatin and pemetrexed, are also utilized, especially for patients not eligible for CRS/HIPEC. Emerging treatment modalities, such as targeted therapies and immunotherapy, are under investigation and may offer additional options in the future. The specific treatment strategy is individualized based on factors like patient performance status, histologic subtype, and extent of disease. Explore how multidisciplinary tumor boards can assist in determining the optimal treatment plan for these complex cases.

Q: How can I differentiate between peritoneal carcinomatosis from a primary ovarian cancer versus a primary gastrointestinal malignancy based on clinical presentation and diagnostic workup?

A: Differentiating peritoneal carcinomatosis originating from ovarian versus gastrointestinal (GI) primary malignancies can be challenging due to overlapping clinical presentations. While both may present with ascites, abdominal pain, and bloating, subtle clues can aid in the initial assessment. Ovarian cancer often presents with a pelvic mass and elevated CA-125 levels, whereas GI malignancies might present with changes in bowel habits, iron deficiency anemia, or elevated CEA or CA 19-9 levels. Imaging modalities, including CT and MRI, are crucial for characterizing the disease burden and potential primary site. Ultimately, definitive diagnosis requires histopathological confirmation, often obtained through laparoscopy or paracentesis with cytology. Consider implementing a comprehensive diagnostic algorithm, including tumor markers, imaging, and tissue biopsy, to accurately identify the primary source and guide appropriate management.

Quick Tips

Practical Coding Tips
  • Code primary site, C78.6
  • Specify histology, morphology
  • Document ascites, mets details
  • Use laterality codes if applicable
  • Consider surgical explore codes

Documentation Templates

Patient presents with symptoms suggestive of peritoneal cancer, including abdominal pain, distension, ascites, nausea, vomiting, and weight loss.  Physical examination reveals abdominal tenderness, palpable masses, and evidence of fluid accumulation.  Diagnostic workup includes CT scan of the abdomen and pelvis demonstrating peritoneal thickening, nodularity, and ascites, consistent with peritoneal carcinomatosis.  Laboratory findings may include elevated CA-125 levels, although this is not diagnostic.  Paracentesis and cytology confirm the presence of malignant cells.  Differential diagnoses considered include ovarian cancer with peritoneal metastasis, primary peritoneal mesothelioma, and other intra-abdominal malignancies.  Given the clinical presentation, imaging findings, and cytology results, the diagnosis of peritoneal cancer is established.  The patient was counseled regarding prognosis and treatment options, including cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC), systemic chemotherapy, and palliative care.  Risks and benefits of each treatment modality were discussed, and the patient opted for palliative chemotherapy to manage symptoms.  Referral to oncology and palliative care services initiated.  Follow-up scheduled to assess treatment response and manage symptoms.  ICD-10 code C48.1, malignant neoplasm of peritoneum, is documented.  Patient education provided regarding disease process, treatment plan, and symptom management strategies.  Emphasis placed on the importance of regular follow-up appointments and communication with the healthcare team.