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C48.2
ICD-10-CM
Peritoneal Carcinoma

Find comprehensive information on Peritoneal Carcinoma diagnosis, including clinical documentation requirements, ICD-10 codes (C48, C78), medical coding guidelines, and healthcare resources. Learn about peritoneal cancer staging, treatment options, and prognosis. This resource provides essential information for physicians, coders, and healthcare professionals involved in the diagnosis and management of Peritoneal Carcinoma. Explore relevant medical terminology, clinical findings, and diagnostic criteria for accurate and efficient documentation and coding.

Also known as

Peritoneal Cancer
Peritoneal Carcinomatosis

Diagnosis Snapshot

Key Facts
  • Definition : Cancer affecting the peritoneum (abdominal lining), often originating from other cancers.
  • Clinical Signs : Abdominal pain, swelling (ascites), bloating, nausea, weight loss, bowel changes.
  • Common Settings : Oncology clinics, hospitals, palliative care settings, surgical centers.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC C48.2 Coding
C48

Peritoneum, malignant neoplasm

Malignant cancer of the peritoneum.

C78

Secondary malignant neoplasm of peritoneum

Cancer that has spread to the peritoneum from another site.

C25

Malignant neoplasm of peritoneum

Cancer specifically impacting the peritoneum, not otherwise specified

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the peritoneal carcinoma primary?

  • Yes

    Is it specified as diffuse?

  • No

    Is the primary site known?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Peritoneal Carcinomatosis
Primary Peritoneal Cancer
Pseudomyxoma Peritonei

Documentation Best Practices

Documentation Checklist
  • Peritoneal Carcinoma ICD-10 C48
  • Primary site or secondary metastasis documented
  • Histological confirmation required (biopsy type)
  • Ascites, abdominal masses: document location, size
  • Disease stage (TNM) based on imaging/pathology

Coding and Audit Risks

Common Risks
  • Primary Site Misidentification

    Incorrect coding due to misidentifying the primary site of peritoneal carcinoma, leading to inaccurate reporting and reimbursement.

  • Histology Specificity Issues

    Lack of specific histology documentation can lead to coding errors and affect accurate cancer registry data.

  • Malignant Ascites Coding

    Confusion between malignant ascites and peritoneal carcinomatosis may result in inaccurate code assignment and claims processing.

Mitigation Tips

Best Practices
  • Code C78.6 for primary Peritoneal Carcinoma, specify histology.
  • Document precise tumor location, size, mets for accurate staging.
  • Query physicians for clarity on malignant ascites, rule out other primaries.
  • Ensure complete pathology reports with immunohistochemistry markers.
  • Follow NCCN guidelines for treatment, document rationale for variances.

Clinical Decision Support

Checklist
  • Review imaging (CT/MRI) for peritoneal thickening/nodules
  • Check for ascites, abdominal pain, or bowel obstruction
  • Confirm diagnosis with biopsy and histopathology
  • Evaluate CA-125 levels (if applicable)

Reimbursement and Quality Metrics

Impact Summary
  • Peritoneal Carcinoma: Reimbursement and Quality Metrics Impact Summary
  • ICD-10 C48, C78.6: Coding accuracy crucial for optimal reimbursement.
  • HCC 188: Impacts risk adjustment and prospective payments.
  • Surgical resection, chemotherapy: Documentation specificity affects quality scores.
  • Timely, accurate coding minimizes denials, improves hospital revenue cycle.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes for . Our AI-powered assistant ensures compliance and reduces coding errors.

Frequently Asked Questions

Common Questions and Answers

Q: What are the most effective current treatment strategies for managing advanced peritoneal carcinoma, considering both systemic chemotherapy and cytoreductive surgery?

A: Managing advanced peritoneal carcinoma often requires a multimodal approach involving systemic chemotherapy and cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC). Current best practice frequently utilizes platinum-based chemotherapy regimens, such as oxaliplatin or cisplatin, in combination with other agents like fluorouracil or leucovorin. The specific regimen chosen is based on factors including patient performance status, histological subtype, and previous treatment history. CRS and HIPEC aim to remove all visible tumor deposits followed by direct application of heated chemotherapy to the abdominal cavity to eliminate microscopic disease. Selection criteria for CRS/HIPEC are rigorous, considering the extent of disease, patient comorbidities, and surgical expertise. Recent research suggests that neoadjuvant chemotherapy may improve the outcomes of CRS/HIPEC by shrinking tumors and making them more resectable. Explore how factors like peritoneal cancer index (PCI) and completeness of cytoreduction influence prognosis and treatment decisions. Consider implementing a comprehensive evaluation process to determine the suitability of patients for aggressive treatment modalities.

Q: How can I differentiate peritoneal carcinomatosis from other causes of ascites in clinical practice, considering diagnostic challenges and common misdiagnoses?

A: Differentiating peritoneal carcinomatosis from other causes of ascites can be challenging due to overlapping clinical presentations. While physical exam findings like abdominal distension and shifting dullness can raise suspicion, they are not specific. Serum-ascites albumin gradient (SAAG) can be helpful, with a high SAAG suggesting portal hypertension and a low SAAG suggesting other causes like malignancy or infection. Cytology from paracentesis is crucial but may have limited sensitivity, particularly in mucinous carcinomas. Elevated tumor markers like CA-125 or CEA can be suggestive but are not diagnostic. Imaging, specifically CT or MRI of the abdomen and pelvis with intravenous contrast, can help visualize peritoneal thickening, nodularity, and omental caking, characteristic of peritoneal carcinomatosis. Laparoscopy with biopsy provides the definitive diagnosis in cases where non-invasive methods are inconclusive. Learn more about the role of advanced imaging techniques like PET/CT in detecting occult metastatic disease and guiding treatment decisions. Consider implementing a multidisciplinary approach involving gastroenterologists, oncologists, and radiologists to improve diagnostic accuracy.

Quick Tips

Practical Coding Tips
  • Code primary site, then peritoneal mets
  • C78.6 peritoneal carcinomatosis
  • Rule out pseudomyxoma peritonei
  • Document primary cancer origin
  • Histology confirms diagnosis

Documentation Templates

Patient presents with symptoms suggestive of peritoneal carcinoma, including abdominal pain, distension, ascites, nausea, vomiting, and weight loss.  Physical examination reveals abdominal tenderness, palpable masses, and possible hepatomegaly or splenomegaly.  Differential diagnosis includes ovarian cancer, colorectal cancer, appendiceal cancer, mesothelioma, and primary peritoneal serous carcinoma.  Diagnostic workup includes a complete blood count (CBC), comprehensive metabolic panel (CMP), tumor markers such as CA-125, CEA, and CA 19-9,  imaging studies such as CT scan of the abdomen and pelvis, and paracentesis with cytology.  Biopsy, either image-guided or laparoscopic, is essential for definitive diagnosis.  Histopathological examination confirms the diagnosis of peritoneal carcinoma, specifying the histological subtype and grade.  Staging of the disease, based on the extent of peritoneal involvement and the presence of distant metastases, is crucial for treatment planning.  Treatment options for peritoneal carcinoma may include cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC), systemic chemotherapy, palliative care, or a combination thereof.  Patient education regarding prognosis, treatment options, and potential complications is provided.  Follow-up appointments are scheduled for monitoring treatment response, managing side effects, and providing ongoing support.  The patient's overall condition, performance status, and comorbidities are considered in developing the individualized treatment plan.
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