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K74.3
ICD-10-CM
Primary Biliary Cholangitis

Find comprehensive information on Primary Biliary Cholangitis diagnosis, including clinical documentation, medical coding, ICD-10 codes K73.1, and relevant healthcare resources. Learn about PBC symptoms, liver function tests LFTs, AMA antibodies, and treatment options. This resource offers guidance for healthcare professionals on accurate PBC diagnosis coding and best practices for patient care documentation. Explore resources related to biliary tract disease, cholestatic liver disease, and autoimmune hepatitis for a thorough understanding of PBC.

Also known as

Primary Biliary Cirrhosis
Autoimmune Cholangitis

Diagnosis Snapshot

Key Facts
  • Definition : Chronic liver disease with progressive bile duct destruction.
  • Clinical Signs : Fatigue, itching, jaundice, elevated liver enzymes, xanthomas.
  • Common Settings : Outpatient hepatology clinics, gastroenterology offices, transplant centers.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC K74.3 Coding
K73.1

Primary biliary cholangitis

Chronic autoimmune liver disease affecting bile ducts.

K70-K77

Diseases of liver

Covers various liver conditions, including inflammation and cirrhosis.

K80-K87

Disorders of gallbladder, biliary tract

Includes conditions affecting bile storage and flow, like gallstones.

M30-M36

Systemic connective tissue disorders

Autoimmune diseases sometimes associated with PBC.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the diagnosis Primary Biliary Cholangitis?

  • Yes

    Is there cirrhosis?

  • No

    Do not code as Primary Biliary Cholangitis. Review the clinical documentation for alternative diagnosis.

Code Comparison

Related Codes Comparison

When to use each related code

Description
Primary Biliary Cholangitis
Primary Sclerosing Cholangitis
Autoimmune Hepatitis

Documentation Best Practices

Documentation Checklist
  • Elevated alkaline phosphatase
  • Positive antimitochondrial antibody (AMA)
  • Imaging (ultrasound/MRCP) findings
  • Liver biopsy findings (if performed)
  • Exclusion of other liver diseases

Coding and Audit Risks

Common Risks
  • Unspecified PBC Stage

    Coding PBC without staging (K74.3) when clinical documentation supports a specific stage (K74.4, K74.5) leads to undercoding and lost revenue.

  • Overlapping Symptoms

    Incorrectly coding overlapping symptoms (e.g., pruritus, fatigue) separately when they are manifestations of PBC can trigger audits and denials.

  • Missed Associated Conditions

    Failure to capture and code associated conditions like osteoporosis or autoimmune hepatitis with PBC can impact risk adjustment and quality metrics.

Mitigation Tips

Best Practices
  • ICD-10 K74.3, PBC diagnosis: Confirm with AMAs, liver biopsy for staging.
  • CDI: Document ursodeoxycholic acid (UDCA) response for PBC management.
  • HCC surveillance crucial: Implement ultrasound q6 months for early detection.
  • Healthcare compliance: Monitor, document adverse effects of PBC therapies.
  • Coding PBC: Include liver function tests (LFTs), ALP levels for accurate severity.

Clinical Decision Support

Checklist
  • Elevated alkaline phosphatase (ALP)? ICD-10: K73.1
  • Positive antimitochondrial antibody (AMA)? SNOMED CT: 1776003
  • Imaging (e.g., MRCP) confirms biliary changes? CPT: 74183
  • Exclude other cholestatic liver diseases Doc: Differential Diagnosis
  • Liver biopsy considered if diagnosis unclear? ICD-10-PCS: 0FB00ZX

Reimbursement and Quality Metrics

Impact Summary
  • Primary Biliary Cholangitis reimbursement hinges on accurate ICD-10-CM K74.3 coding and appropriate HCC coding for risk adjustment.
  • PBC quality metrics impact: Liver function tests, MELD score reporting influence hospital quality performance.
  • Timely diagnosis coding and biliary imaging documentation improve PBC reimbursement and care quality.
  • Optimize PBC revenue cycle with precise coding, HCC capture, and compliant billing for ursodeoxycholic acid therapy.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes for . Our AI-powered assistant ensures compliance and reduces coding errors.

Quick Tips

Practical Coding Tips
  • Code K74.3 for PBC diagnosis
  • ICD-10-CM K74.3 Primary Biliary Cholangitis
  • Document AMA stage for PBC
  • Liver biopsy findings support K74.3
  • Confirm PBC diagnosis, avoid K74.5

Documentation Templates

Patient presents with complaints consistent with possible primary biliary cholangitis (PBC).  Symptoms reported include fatigue, pruritus, and right upper quadrant discomfort.  Patient denies jaundice, fever, or chills.  Physical examination reveals hepatomegaly with mild tenderness on palpation.  Skin examination shows evidence of xanthelasma.  Laboratory findings demonstrate elevated alkaline phosphatase, elevated gamma-glutamyl transferase (GGT), and the presence of antimitochondrial antibodies (AMA).  Liver function tests (LFTs) show elevated bilirubin and aspartate aminotransferase (AST).  Ultrasound of the abdomen revealed no biliary obstruction.  Diagnosis of primary biliary cholangitis is suspected based on the clinical presentation, serological markers, and imaging findings.  Differential diagnoses include primary sclerosing cholangitis (PSC), autoimmune hepatitis, and drug-induced liver injury.  Plan includes further evaluation with liver biopsy to confirm the diagnosis and stage the disease.  Treatment will be initiated with ursodeoxycholic acid (UDCA) for management of cholestasis and symptomatic relief.  Patient education provided regarding PBC, its progression, and the importance of medication adherence.  Follow-up appointment scheduled to review biopsy results and assess response to therapy.  ICD-10 code K74.3 assigned.  Referral to hepatology specialist considered.  Patient advised to report any worsening symptoms, such as jaundice, dark urine, or light-colored stools.
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