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E78.00
ICD-10-CM
Pure Hypercholesterolemia

Find information on pure hypercholesterolemia diagnosis, including clinical documentation, ICD-10 codes (E78.0), medical coding guidelines, and healthcare resources. Learn about familial hypercholesterolemia, genetic testing, cholesterol management, lipid panel interpretation, and treatment options for high cholesterol. This resource supports healthcare professionals in accurate diagnosis and coding for pure hypercholesterolemia.

Also known as

High Cholesterol
LDL Hypercholesterolemia

Diagnosis Snapshot

Key Facts
  • Definition : Genetic disorder causing high cholesterol even with a healthy lifestyle.
  • Clinical Signs : Often asymptomatic, but high LDL cholesterol levels are key.
  • Common Settings : Primary care, cardiology, lipid clinics.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC E78.00 Coding
E78.0

Pure hypercholesterolemia

Elevated cholesterol levels without other known cause.

E78.1

Mixed hyperlipidemia

Elevated cholesterol and other lipids in the blood.

E78.2

Other hypercholesterolemia

Elevated cholesterol not classified elsewhere.

Z83.42

Family history of hypercholesterolemia

Personal history of familial high cholesterol.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the hypercholesterolemia pure (not secondary)?

  • Yes

    Is it familial hypercholesterolemia?

  • No

    Do NOT code as pure hypercholesterolemia. Code underlying cause.

Code Comparison

Related Codes Comparison

When to use each related code

Description
Pure Hypercholesterolemia
Familial Combined Hyperlipidemia
Polygenic Hypercholesterolemia

Documentation Best Practices

Documentation Checklist
  • Elevated LDL-C documented, specify units.
  • Exclude secondary causes hypercholesterolemia.
  • Family history of hypercholesterolemia noted.
  • Physical exam findings if applicable.
  • Assess and document patient's CVD risk.

Coding and Audit Risks

Common Risks
  • Unspecified Dyslipidemia

    Coding E78.0 for pure hypercholesterolemia without specifying the type (familial vs. acquired) leads to lower reimbursement and data inaccuracy.

  • Missing Family History

    Failing to document family history of hypercholesterolemia can impact accurate diagnosis of familial hypercholesterolemia (E78.01) and relevant genetic testing.

  • Unconfirmed Diagnosis

    Coding hypercholesterolemia without supporting lab results or documentation of elevated LDL levels poses audit risks and compliance issues.

Mitigation Tips

Best Practices
  • ICD-10 E78.0, family history crucial for FH diagnosis documentation.
  • LDL-C, HDL-C, Triglycerides: Document all lipid panel results for accurate E78.0 coding.
  • Assess/document FH severity (homozygous/heterozygous) for optimal CDI, impacting HCC coding.
  • Genetic testing (e.g., LDLR, APOB, PCSK9) strengthens FH diagnosis, improves risk adjustment.
  • Comply with NCLEX guidelines: Document patient education on lifestyle changes and medication adherence.

Clinical Decision Support

Checklist
  • 1. LDL-C elevated, other lipids normal (ICD-10 E78.0)
  • 2. FH ruled out (family history, genetic testing)
  • 3. Secondary causes excluded (meds, hypothyroidism)
  • 4. Assess CVD risk (Framingham, Pooled Cohort)

Reimbursement and Quality Metrics

Impact Summary
  • Pure hypercholesterolemia reimbursement: ICD-10 E78.0 impacts MS-DRG assignment, affecting hospital payments.
  • Coding accuracy crucial: E78.0 vs. mixed hyperlipidemia (E78.2) ensures correct reimbursement, avoids denials.
  • Quality metrics: Elevated LDL-C directly impacts HEDIS measures for cholesterol management, affecting hospital ratings.
  • Hospital reporting: Accurate E78.0 coding essential for precise prevalence data, impacting resource allocation.

Streamline Your Medical Coding

Let S10.AI help you select the most accurate ICD-10 codes. Our AI-powered assistant ensures compliance and reduces coding errors.

Quick Tips

Practical Coding Tips
  • Document family Hx hypercholesterolemia
  • Exclude secondary causes E78.0
  • Specify type: I, IIa, IIb, III, IV
  • Code primary hypercholesterolemia E78.0

Documentation Templates

Patient presents with primary hypercholesterolemia, also known as familial hypercholesterolemia, characterized by significantly elevated LDL cholesterol levels.  Family history is positive for high cholesterol and premature cardiovascular disease.  The patient denies any symptoms specifically attributable to hypercholesterolemia, such as xanthomas or xanthelasmas.  Physical examination reveals no overt signs of hyperlipidemia.  Current lipid panel demonstrates elevated LDL cholesterol exceeding the diagnostic threshold for pure hypercholesterolemia, with triglycerides and HDL cholesterol within normal limits.  This diagnosis is consistent with the criteria for familial hypercholesterolemia without secondary causes such as hypothyroidism, nephrotic syndrome, or medication-induced hyperlipidemia.  The patient has been counseled on lifestyle modifications including a therapeutic lifestyle changes diet low in saturated and trans fats, regular exercise, and weight management.  Pharmacological intervention with a statin, specifically atorvastatin, has been initiated to manage LDL cholesterol levels and reduce cardiovascular risk.  The patient will be closely monitored for treatment efficacy and potential adverse effects.  Follow-up lipid panel and clinical evaluation scheduled in three months.  ICD-10 code E78.01, pure hypercholesterolemia, is assigned.  Medical billing codes for lipid panel and evaluation and management services are documented.  Patient education provided regarding cholesterol management, statin therapy, and the importance of adherence to treatment plan.