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D64.9
ICD-10-CM
Severe Anemia

Learn about severe anemia diagnosis, including clinical documentation requirements, ICD-10 codes (D50-D64), medical coding guidelines, and healthcare management strategies. Find information on symptoms, lab values (hemoglobin, hematocrit, RBC), treatment options, and complications associated with severe anemia for accurate and comprehensive clinical care. This resource addresses common search queries related to anemia diagnosis, severity classification, and best practices for healthcare professionals.

Also known as

Acute Anemia
Chronic Anemia
Iron Deficiency Anemia

Diagnosis Snapshot

Key Facts
  • Definition : A significant decrease in red blood cells, hemoglobin, or hematocrit, leading to reduced oxygen delivery to tissues.
  • Clinical Signs : Fatigue, weakness, shortness of breath, pale skin, dizziness, headache, rapid heart rate.
  • Common Settings : Primary care, urgent care, emergency room, hematology clinic.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC D64.9 Coding
D50-D53

Nutritional anemias

Anemias caused by dietary deficiencies or impaired absorption.

D60-D64

Aplastic and other anemias

Conditions affecting red blood cell production, including aplastic anemia.

D55-D59

Hemolytic anemias

Anemias characterized by premature destruction of red blood cells.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the anemia due to blood loss (acute or chronic)?

  • Yes

    Acute blood loss?

  • No

    Is it due to nutritional deficiency?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Severe anemia
Iron deficiency anemia
B12 deficiency anemia

Documentation Best Practices

Documentation Checklist
  • Document specific Hb level below threshold for severe anemia.
  • Specify symptoms (fatigue, pallor, dyspnea, etc.)
  • Underlying cause if known (e.g., blood loss, iron deficiency)
  • Date of diagnosis and diagnostic method used.
  • Treatment plan including any transfusions given.

Mitigation Tips

Best Practices
  • Document precise hemoglobin/hematocrit for ICD-10-CM code specificity (D64.8).
  • Ensure complete blood count (CBC) and peripheral smear review for anemia severity.
  • Query physician for etiology/cause of anemia for accurate CDI and coding.
  • Review iron studies, vitamin B12, folate levels for appropriate coding (e.g., D50.8, D51, D53.0).
  • Adhere to HCC/RAF coding guidelines for risk adjustment accuracy in anemia cases.

Clinical Decision Support

Checklist
  • Verify Hb level <7 g/dL (ICD-10-CM D64.8)
  • Confirm symptoms: fatigue, pallor, dyspnea (SNOMED CT 248582009)
  • Evaluate for underlying cause: bleeding, diet, CKD (ICD-10-CM)
  • Review blood smear for RBC morphology (SNOMED CT 125551008)

Reimbursement and Quality Metrics

Impact Summary
  • Severe Anemia reimbursement hinges on accurate ICD-10-CM coding (D64.8) and proper documentation supporting medical necessity for optimal payer coverage.
  • Quality metrics impacted: Patient blood management (PBM), hospital-acquired anemia (HAA), 30-day readmission rates for anemia complications, and patient-reported outcomes.
  • Coding errors for severe anemia can lead to claim denials, impacting revenue cycle management and hospital financial performance.
  • Timely diagnosis and treatment documentation improves anemia quality reporting, demonstrating value-based care and positively impacting reimbursement.

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Frequently Asked Questions

Common Questions and Answers

Q: What are the most effective diagnostic strategies for differentiating between various causes of severe anemia in adult patients?

A: Diagnosing severe anemia (hemoglobin <7 g/dL) requires a systematic approach to differentiate various etiologies. Begin with a thorough patient history focusing on symptoms (fatigue, shortness of breath, pallor), dietary habits, medication use, and family history of blood disorders. Physical examination should assess for signs of bleeding (e.g., petechiae, ecchymosis), splenomegaly, or lymphadenopathy. Initial laboratory investigations should include a complete blood count (CBC) with red blood cell indices (MCV, MCH, MCHC), reticulocyte count, peripheral blood smear, iron studies (serum iron, ferritin, transferrin saturation), vitamin B12 and folate levels. Further testing based on initial findings may include bone marrow biopsy, hemoglobin electrophoresis, direct antiglobulin test (DAT), or specific genetic tests. Consider implementing a diagnostic algorithm based on the MCV (microcytic, normocytic, or macrocytic) to guide further investigations and narrow down potential causes. Explore how a comprehensive approach can improve diagnostic accuracy and patient outcomes in cases of severe anemia.

Q: How should I manage a patient presenting with severe anemia and acute symptoms like shortness of breath or chest pain in the emergency department?

A: Managing a patient with severe anemia (hemoglobin <7 g/dL) and acute symptoms requires rapid assessment and intervention. Prioritize airway, breathing, and circulation (ABCs). Administer supplemental oxygen and initiate cardiac monitoring. If the patient is hemodynamically unstable (hypotension, tachycardia), intravenous (IV) fluid resuscitation with crystalloids should be initiated promptly, followed by red blood cell transfusion if necessary. Simultaneously, identify the underlying cause of the anemia through history, physical exam, and point-of-care testing, including CBC, peripheral smear, and type and screen. Consider implementing a blood conservation strategy to minimize further blood loss. Learn more about the emergency management protocols for severe anemia and best practices for red blood cell transfusion.

Quick Tips

Practical Coding Tips
  • Document Hgb/Hct for anemia severity
  • Specify type of anemia (e.g., iron deficiency)
  • Code underlying cause if known
  • Query physician if documentation unclear
  • Review payer guidelines for anemia coding

Documentation Templates

Patient presents with severe anemia, characterized by significantly decreased hemoglobin levels, resulting in symptoms such as fatigue, weakness, shortness of breath, pallor, dizziness, and palpitations.  Laboratory findings confirm severe anemia, with hemoglobin concentration below 7.0 g/dL (or equivalent measure appropriate for the patient's age and sex).  The patient's medical history, including medication list, family history of anemia, dietary habits, and any recent bleeding episodes, was thoroughly reviewed.  Differential diagnosis considerations include iron deficiency anemia, vitamin B12 deficiency anemia, folate deficiency anemia, aplastic anemia, hemolytic anemia, chronic disease anemia, and anemia of chronic kidney disease.  Further diagnostic testing, such as complete blood count (CBC) with differential, peripheral blood smear review, iron studies, vitamin B12 levels, folate levels, reticulocyte count, haptoglobin, direct antiglobulin test (DAT), and renal function tests, may be necessary to identify the underlying etiology of the severe anemia.  Initial management includes addressing immediate symptoms and ensuring hemodynamic stability.  Treatment plans will be tailored based on the underlying cause and severity of the anemia and may include iron supplementation, vitamin B12 injections, folate supplementation, blood transfusion, erythropoiesis-stimulating agents (ESAs), or other disease-specific therapies.  Patient education on anemia management, dietary recommendations, medication adherence, and potential complications will be provided.  Follow-up appointments are scheduled to monitor hemoglobin levels, treatment response, and overall clinical status.  ICD-10-CM code D64.9 (Anemia, unspecified) or a more specific code based on the identified etiology will be assigned.  Appropriate medical billing codes for laboratory tests, procedures, and office visits will be used.
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