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A49.09
ICD-10-CM
Staphylococcus epidermidis Infection

Learn about Staphylococcus epidermidis infection diagnosis, including clinical manifestations, laboratory identification, ICD-10 codes (e.g., A49.01, other specified staphylococcal infections), and SNOMED CT concepts. This resource provides information for healthcare professionals on documenting, coding, and managing S. epidermidis infections, covering coagulase-negative staphylococci, bloodstream infections, and device-related infections. Find guidance on appropriate antibiotic treatment and infection prevention strategies for healthcare settings.

Also known as

S. epidermidis infection
Coagulase-negative Staphylococcus infection

Diagnosis Snapshot

Key Facts
  • Definition : Infection caused by the bacterium Staphylococcus epidermidis, commonly found on the skin.
  • Clinical Signs : Redness, swelling, pain, warmth at the infection site. May cause fever or pus.
  • Common Settings : Catheter sites, surgical wounds, implanted medical devices, prosthetic joints.

Related ICD-10 Code Ranges

Complete code families applicable to AAPC A49.09 Coding
A49.01

Staphylococcal infection, unspecified

Infection due to Staphylococcus, not otherwise specified.

B95.8

Other bacterial agents as the cause of diseases

Diseases classified elsewhere but caused by other bacterial agents.

T81.4XXA

Infection following a procedure

Infection following a procedure, initial encounter.

Code-Specific Guidance

Decision Tree for

Follow this step-by-step guide to choose the correct ICD-10 code.

Is the S. epidermidis infection localized?

  • Yes

    Specify site of infection.

  • No

    Is it systemic/bacteremia?

Code Comparison

Related Codes Comparison

When to use each related code

Description
Staph epidermidis infection
Staph aureus infection
Streptococcal infection

Documentation Best Practices

Documentation Checklist
  • Confirmed Staphylococcus epidermidis infection diagnosis
  • Document infection site, e.g., bloodstream, surgical wound
  • Culture and sensitivity report details
  • Patient symptoms and clinical presentation
  • Treatment plan, including antibiotics administered

Coding and Audit Risks

Common Risks
  • Unspecified Site

    Coding S. epidermidis without specifying the infection site leads to inaccurate severity and reimbursement. Use site-specific codes.

  • Device-Related Omission

    Failing to code device association when S. epidermidis is related to a device (e.g., catheter) impacts quality metrics and data accuracy.

  • Methicillin Resistance

    Not documenting or coding methicillin resistance (MRSE) status affects treatment and infection control tracking. Clarify susceptibility.

Mitigation Tips

Best Practices
  • Document S. epidermidis isolate source (e.g., catheter)
  • Specify infection type (e.g., bloodstream, surgical site)
  • Perform antimicrobial susceptibility testing (AST)
  • Review CDI guidelines for accurate coding (e.g., ICD-10)
  • Ensure compliance with device-related infection protocols

Clinical Decision Support

Checklist
  • Coagulase-negative Staph isolated? (ICD-10 B95.8)
  • Implantable device or catheter present? Document type & location.
  • Local signs of infection (erythema, warmth, tenderness)?
  • Blood cultures positive for S. epidermidis? Document if contaminant likely.
  • Consider other diagnoses if no device/catheter & no local signs.

Reimbursement and Quality Metrics

Impact Summary
  • Staphylococcus epidermidis Infection reimbursement hinges on accurate ICD-10-CM (A41.1 or other relevant codes) and CPT coding for procedures like debridement or drainage.
  • Quality metrics impacted: Surgical Site Infection (SSI) rates, central line-associated bloodstream infection (CLABSI) if applicable, readmission rates.
  • Coding accuracy directly affects MS-DRG assignment and subsequent hospital reimbursement for S. epidermidis infections.
  • Proper documentation of infection severity and treatment influences hospital quality reporting and potential value-based payments.

Streamline Your Medical Coding

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Frequently Asked Questions

Common Questions and Answers

Q: How to differentiate Staphylococcus epidermidis contamination from true infection in blood cultures?

A: Differentiating Staphylococcus epidermidis contamination from true bacteremia can be challenging. Consider the following factors: Multiple positive blood cultures, especially from separate venipunctures, strongly suggest true infection. Clinical symptoms consistent with infection, such as fever, chills, hypotension, or localized signs of infection at a catheter site, further support the diagnosis. In contrast, a single positive blood culture with no accompanying symptoms is more likely due to contamination, especially if the organism is isolated from a peripheral venipuncture. Coagulase-negative staphylococci, including S. epidermidis, are common skin commensals and frequent contaminants in blood cultures. Microbial identification and antibiotic susceptibility testing are crucial, as true infections require targeted antimicrobial therapy. Explore how repeat blood cultures and clinical correlation can enhance diagnostic accuracy. Consider implementing best practices for aseptic blood collection technique to minimize contamination rates.

Q: What are the recommended treatment options for Staphylococcus epidermidis prosthetic joint infection?

A: Staphylococcus epidermidis prosthetic joint infection (PJI) often requires a multi-faceted approach. Due to biofilm formation and antibiotic resistance, treatment typically involves both surgical and antimicrobial interventions. Debridement, antibiotics, and implant retention (DAIR) may be considered in early or less severe infections. One- or two-stage revision arthroplasty is often necessary, especially in chronic or complex cases. Antibiotic therapy is guided by culture and susceptibility testing, with vancomycin, daptomycin, linezolid, or rifampin often used. The duration of antibiotic therapy is typically prolonged, often for several weeks following surgery. Learn more about biofilm-active antibiotics and their role in managing PJI. Consider implementing peri-operative antibiotic prophylaxis protocols to minimize infection risk in joint replacement surgery.

Quick Tips

Practical Coding Tips
  • Code S. epidermidis infection site
  • Document culture/sensitivity results
  • Specify device-related infection if applicable
  • Use additional codes for complications
  • Consider A49.01 for unspecified S. epidermidis

Documentation Templates

Patient presents with signs and symptoms suggestive of a Staphylococcus epidermidis infection.  Presenting complaints include localized erythema, warmth, tenderness, and possible purulent drainage.  The suspected infection site is [Specify location, e.g., surgical wound, intravenous catheter site, prosthetic joint].  Onset of symptoms occurred approximately [Number] days ago.  Patient's medical history includes [Relevant comorbidities, e.g., diabetes mellitus, recent surgery, immunosuppression].  Relevant medications include [List current medications].  Allergies include [List allergies].  Physical examination reveals [Detailed findings, e.g., induration, fluctuance, fever].  Differential diagnosis includes cellulitis, abscess, and other bacterial infections.  Preliminary diagnosis of Staphylococcus epidermidis infection is based on clinical presentation.  Laboratory tests ordered include wound culture and sensitivity, complete blood count (CBC) with differential, and blood cultures if systemic infection is suspected.  Treatment plan includes [Specify treatment, e.g., incision and drainage, removal of foreign body, antibiotic therapy with vancomycin, cefazolin, or other appropriate agent based on culture and sensitivity results].  Patient education provided regarding wound care, medication administration, and signs and symptoms of worsening infection.  Follow-up appointment scheduled in [Number] days to assess treatment response.  ICD-10 code [Appropriate ICD-10 code, e.g., T82.8XXA for infection due to indwelling medical device] and CPT codes for procedures performed [e.g., incision and drainage, 10060, 10061] will be documented for medical billing and coding purposes.  Coagulase-negative staphylococcal infection, healthcare-associated infection, and antimicrobial stewardship are additional keywords relevant to this case.