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ICD-10-CM · K81.2GeneralSystemic

Acalculous Cholecystitis

Learn about acalculous cholecystitis, also known as gallbladder inflammation without stones. This page covers diagnosis, clinical documentation, and medical coding for non-calculous cholecystitis, a serious condition requiring prompt medical attention. Find information relevant to healthcare professionals, including ICD-10 codes and best practices for accurate documentation.

Also known as
Gallbladder inflammation without stonesNon-calculous cholecystitis
Definition

Gallbladder inflammation without gallstones.

Clinical signs

Right upper quadrant pain, fever, nausea, vomiting, positive Murphy's sign.

Common settings

Critical illness, post-surgery, trauma, burns, prolonged fasting.

Related Codes

ICD-10 Code Families

Complete code families applicable to K81.2

K81.0-K81.1
Acalculous cholecystitis
K80-K87
Disorders of gallbladder, biliary tract
K87.0-K87.89
Other specified diseases of gallbladder
Code Comparison

When to use each related code

DescriptionWhen to use
Gallbladder inflammation without stonesUse for acute or chronic gallbladder inflammation when gallstones are NOT present. Consider infection, ischemia, or trauma.
Gallbladder inflammation with stonesUse when gallstones ARE present and causing gallbladder inflammation. Most common type of cholecystitis.
Gallbladder dysfunction without inflammationUse for biliary dyskinesia or chronic acalculous gallbladder disease where the gallbladder is not functioning properly but not inflamed.
Documentation

Best-practice checklist

  • Document gallbladder wall thickening, distension, or pericholecystic fluid.
  • Specify absence of gallstones on imaging (ultrasound, CT, MRI).
  • Detail patient's clinical presentation: RUQ pain, fever, nausea, vomiting.
  • Note any risk factors: sepsis, trauma, burns, TPN, prolonged fasting.
  • Include labs: elevated WBC, abnormal LFTs, positive Murphy's sign.
Coding & Audit Risks

Common pitfalls to avoid

Unspecified Cholecystitis

Coding K87.0 (acute) or K87.1 (chronic) without documented acalculous etiology risks inaccurate reimbursement.

Missing Critical Care

Failing to document critical care services for severe acalculous cholecystitis can lead to lost revenue.

Conflicting Documentation

Discrepancies between physician notes and imaging reports regarding stone presence can create coding and billing errors.

Mitigation

Best-practice tips

  • 01Timely diagnosis via imaging (ultrasound, CT) crucial for acalculous cholecystitis.
  • 02Document gallbladder wall thickening, pericholecystic fluid for accurate coding.
  • 03Correlate clinical findings (fever, RUQ pain) with imaging for CDI of acalculous cholecystitis.
  • 04Early intervention (antibiotics, cholecystostomy) key to mitigate complications.
  • 05Monitor patient closely for disease progression and document response to treatment.
Clinical Decision Support

Step-by-step checklist

  1. 1

    Verify RUQ pain, fever, or elevated WBCs documented.

  2. 2

    Confirm imaging (ultrasound, CT, HIDA) supports diagnosis.

  3. 3

    Check for predisposing factors (critical illness, TPN).

  4. 4

    Document gallbladder wall thickening or pericholecystic fluid.

  5. 5

    Exclude alternative diagnoses (e.g., pancreatitis, hepatitis).

Documentation Template

Ready-to-paste narrative

Patient presents with signs and symptoms suggestive of acalculous cholecystitis, a diagnosis of gallbladder inflammation without gallstones.  The patient reports right upper quadrant pain, which may be described as sharp, cramping, or dull and aching.  Fever, nausea, vomiting, and anorexia are also noted.  Physical examination reveals tenderness in the right upper quadrant, and Murphy's sign may be positive.  Laboratory findings may indicate elevated white blood cell count, C-reactive protein, and liver function tests.  Imaging studies, such as abdominal ultrasound or CT scan of the abdomen and pelvis, are essential for diagnosis and may reveal gallbladder wall thickening, pericholecystic fluid, or distension.  Differential diagnoses include biliary colic, acute pancreatitis, and peptic ulcer disease.  Given the clinical presentation and absence of gallstones on imaging, the diagnosis of acalculous cholecystitis is suspected.  Treatment for acalculous cholecystitis typically involves supportive care, including intravenous fluids, pain management, and antibiotics.  Cholecystectomy, either laparoscopic or open, may be necessary if the patient's condition does not improve with conservative management or if complications arise.  The patient's clinical status will be closely monitored for signs of improvement or potential complications such as gallbladder perforation or gangrene.
FAQs

Common questions and answers

How can I differentiate acalculous cholecystitis from calculous cholecystitis in critically ill patients with vague abdominal pain?+

Differentiating acalculous cholecystitis (gallbladder inflammation without stones) from calculous cholecystitis in critically ill patients can be challenging due to overlapping symptoms and the patients' often precarious state. While both present with right upper quadrant pain, fever, and leukocytosis, the absence of gallstones on imaging in acalculous cholecystitis is key. However, relying solely on imaging can be misleading. Consider incorporating bedside ultrasound to rapidly assess gallbladder wall thickening, pericholecystic fluid, and a positive sonographic Murphy's sign, especially in patients unable to undergo immediate CT or MRI. Furthermore, evaluating risk factors like recent surgery, trauma, prolonged fasting, total parenteral nutrition (TPN), or sepsis can increase suspicion for acalculous cholecystitis. Labs may show elevated alkaline phosphatase and bilirubin, although these aren't specific. Given the higher morbidity and mortality associated with acalculous cholecystitis in critically ill patients, early diagnosis and intervention are crucial. Explore how serial imaging and clinical assessments can improve diagnostic accuracy and guide appropriate management strategies like percutaneous cholecystostomy or, if feasible, cholecystectomy.

What are the best imaging modalities for diagnosing acalculous cholecystitis, and how should I interpret the findings in a patient with suspected gallbladder inflammation without stones?+

Ultrasound, CT, and hepatobiliary iminodiacetic acid (HIDA) scans are the primary imaging modalities for diagnosing acalculous cholecystitis (gallbladder inflammation without stones). Ultrasound can demonstrate gallbladder wall thickening (>4mm), pericholecystic fluid, and a positive sonographic Murphy's sign, suggestive of inflammation. However, its sensitivity can be limited in critically ill patients. CT scans can reveal gallbladder wall edema, distension, and pericholecystic fluid or abscesses, offering a more comprehensive view of the surrounding structures. HIDA scans are particularly useful when ultrasound and CT findings are equivocal. Non-visualization of the gallbladder on HIDA scan, suggesting cystic duct obstruction, is highly suggestive of acalculous cholecystitis. Interpreting these findings requires careful correlation with the patient's clinical picture, including risk factors like recent surgery, trauma, or sepsis. Consider implementing a multi-modal imaging approach for a more accurate diagnosis and to rule out other differential diagnoses like acute hepatitis or pancreatitis. Learn more about the sensitivity and specificity of different imaging modalities in the context of acalculous cholecystitis.

What are the evidence-based management strategies for acalculous cholecystitis, considering both percutaneous and surgical interventions?+

Managing acalculous cholecystitis requires a multidisciplinary approach, factoring in the patient's clinical stability and the severity of the inflammation. Initial management often involves supportive care with intravenous fluids, antibiotics covering enteric organisms, and pain control. For critically ill patients or those with contraindications to surgery, percutaneous cholecystostomy under image guidance is often the preferred initial intervention. This procedure provides drainage of the infected gallbladder, relieving pressure and allowing for stabilization before considering definitive surgical intervention. For patients who are stable and fit for surgery, cholecystectomy remains the gold standard treatment. Laparoscopic cholecystectomy is generally preferred for its minimally invasive nature, leading to shorter hospital stays and faster recovery. However, open cholecystectomy may be necessary in complex cases or if significant inflammation obscures the laparoscopic field. Consider implementing a staged approach, starting with percutaneous drainage followed by delayed cholecystectomy once the patient's condition improves. Learn more about optimizing antibiotic coverage based on local resistance patterns and individual patient factors to minimize complications and improve outcomes.

Clinical accuracy: This information is provided for documentation and coding guidance and should not replace professional medical judgment.

Coding standard: ICD-10-CM, current FY guidelines.