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ICD-10-CM · E11.00GeneralSystemic

Hyperosmolar Hyperglycemic State

Find comprehensive information on Hyperosmolar Hyperglycemic State diagnosis, including clinical documentation tips, ICD-10 codes (E11.1, E14.1), medical coding guidelines, and healthcare best practices for HHS management. Learn about HHS symptoms, treatment protocols, and the differences between HHS and DKA. This resource provides essential information for healthcare professionals, clinicians, and medical coders seeking accurate and up-to-date guidance on Hyperosmolar Hyperglycemic Syndrome.

Also known as
HHSHyperosmolar Non-Ketotic StateHyperosmolar Hyperglycemic Nonketotic Syndrome
Definition

Severe hyperglycemia with dehydration and altered mental status, but without significant ketoacidosis.

Clinical signs

High blood sugar (often >600 mg/dL), dry mouth, extreme thirst, frequent urination, confusion, drowsiness.

Common settings

Elderly patients with type 2 diabetes, often triggered by infection, illness, or certain medications.

Related Codes

ICD-10 Code Families

Complete code families applicable to E11.00

E11-E14
Diabetes mellitus
E86
Volume depletion
E87
Other disorders of fluid, electrolyte, and acid-base balance
Code Comparison

When to use each related code

DescriptionWhen to use
Hyperosmolar Hyperglycemic StateVery high blood sugar, severe dehydration, no ketones. Often in older adults with type 2 diabetes.
Diabetic KetoacidosisHigh blood sugar, ketones, metabolic acidosis. Common in type 1, sometimes type 2 diabetes.
Uncontrolled Diabetes MellitusPersistently elevated blood glucose without specific acute complication like HHS or DKA.
Documentation

Best-practice checklist

  • ✓Document plasma glucose >600 mg/dL
  • ✓Document serum osmolality >320 mOsm/kg
  • ✓Document profound dehydration findings
  • ✓Exclude ketoacidosis and lactic acidosis
  • ✓Document altered mental status or neurological signs
Mitigation

Best-practice tips

  • 01Document blood glucose, osmolarity, ketones for HHS diagnosis (ICD-10 E14.10)
  • 02Ensure CDI of dehydration status, electrolyte imbalances for accurate coding.
  • 03Monitor, document, and code neurologic status changes in HHS (ICD-10 G93.4)
  • 04Timely fluid resuscitation, insulin therapy documentation for compliance, coding.
  • 05Educate patients on sick day management to prevent HHS readmissions (ICD-10 Z71.3)
Clinical Decision Support

Step-by-step checklist

  1. 1

    Plasma glucose >600 mg/dL (ICD-10 E14.10)

  2. 2

    Serum osmolality >320 mOsm/kg (SNOMED CT 714539000)

  3. 3

    Absent/mild ketosis (patient safety check)

  4. 4

    Altered mental status documented (E/M coding)

Documentation Template

Ready-to-paste narrative

Patient presents with hyperosmolar hyperglycemic state (HHS), a serious metabolic complication of diabetes mellitus, typically type 2 diabetes.  Onset was gradual with presenting symptoms including polyuria, polydipsia, polyphagia, and weight loss over the past [Number] daysweeks.  The patient exhibits signs of severe dehydration, including dry mucous membranes, tachycardia, and hypotension.  Neurological symptoms such as altered mental status, ranging from confusion to coma, are also noted.  Laboratory findings reveal marked hyperglycemia (blood glucose greater than 600 mgdL), elevated serum osmolality (greater than 320 mOsmkg), and absence of significant ketoacidosis.  Serum electrolytes show hypernatremia, hypokalemia, and elevated blood urea nitrogen (BUN) and creatinine, indicative of acute kidney injury secondary to dehydration.  Urinalysis reveals glucosuria without significant ketonuria.  Differential diagnoses considered include diabetic ketoacidosis (DKA), hyperglycemic hyperosmolar nonketotic syndrome (HHNS), and dehydration due to other causes.  The diagnosis of HHS is based on the clinical presentation, hyperglycemia, hyperosmolality, and absence of significant ketosis.  Treatment plan includes aggressive fluid resuscitation with intravenous isotonic saline to correct dehydration and restore intravascular volume, continuous intravenous insulin infusion to lower blood glucose levels, and close monitoring of electrolytes, renal function, and mental status.  Electrolyte imbalances, particularly potassium, will be corrected as needed.  The patient will be closely monitored for potential complications such as cerebral edema, acute kidney injury, and thromboembolic events.  Patient education will focus on diabetes management, including medication adherence, blood glucose monitoring, and recognition of early signs and symptoms of HHS.  Coding will likely include ICD-10-CM code E11.10 for type 2 diabetes mellitus with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma, and additional codes to reflect complications such as acute kidney injury.  Medical billing will reflect the level of care provided, including intensive care unit (ICU) admission if required.

Clinical accuracy: This information is provided for documentation and coding guidance and should not replace professional medical judgment.

Coding standard: ICD-10-CM, current FY guidelines.