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Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
D80-D89

Certain disorders involving the immune mechanism

Explore comprehensive insights into ICD-10 code range D80-D89, covering certain disorders involving the immune mechanism. Enhance clinical documentation accuracy and coding specificity with detailed guidelines for conditions like immunodeficiencies and autoimmune diseases. Perfect for healthcare professionals seeking to optimize patient records and improve billing accuracy.

About This Range
100+
Total codes
83+
Billable codes
17+
Non-billable codes
3
Chapters
Codes in this Range (100+)
Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism Range: D50-D89
D80
Immunodeficiency with predominantly antibody defects
D80.0
Hereditary hypogammaglobulinemia
Billable
D80.1
Nonfamilial hypogammaglobulinemia
Billable
D80.2
Selective deficiency of immunoglobulin A [IgA]
Billable
D80.3
Selective deficiency of immunoglobulin G [IgG] subclasses
Billable
D80.4
Selective deficiency of immunoglobulin M [IgM]
Billable
D80.5
Immunodeficiency with increased immunoglobulin M [IgM]
Billable
D80.6
Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
Billable
D80.7
Transient hypogammaglobulinemia of infancy
Billable
D80.8
Other immunodeficiencies with predominantly antibody defects
Billable
D80.9
Immunodeficiency with predominantly antibody defects, unspecified
Billable
D81
Combined immunodeficiencies
D81.0
Severe combined immunodeficiency [SCID] with reticular dysgenesis
Billable
D81.1
Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
Billable
D81.2
Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
Billable
D81.3
Adenosine deaminase [ADA] deficiency
D81.30
Adenosine deaminase deficiency, unspecified
Billable
D81.31
Severe combined immunodeficiency due to adenosine deaminase deficiency
Billable
D81.32
Adenosine deaminase 2 deficiency
Billable
D81.39
Other adenosine deaminase deficiency
Billable
D81.4
Nezelof's syndrome
Billable
D81.5
Purine nucleoside phosphorylase [PNP] deficiency
Billable
D81.6
Major histocompatibility complex class I deficiency
Billable
D81.7
Major histocompatibility complex class II deficiency
Billable
D81.8
Other combined immunodeficiencies
D81.81
Biotin-dependent carboxylase deficiency
D81.810
Biotinidase deficiency
Billable
D81.818
Other biotin-dependent carboxylase deficiency
Billable
D81.819
Biotin-dependent carboxylase deficiency, unspecified
Billable
D81.82
Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
Billable
D81.89
Other combined immunodeficiencies
Billable
D81.9
Combined immunodeficiency, unspecified
Billable
D82
Immunodeficiency associated with other major defects
D82.0
Wiskott-Aldrich syndrome
Billable
D82.1
Di George's syndrome
Billable
D82.2
Immunodeficiency with short-limbed stature
Billable
D82.3
Immunodeficiency following hereditary defective response to Epstein-Barr virus
Billable
D82.4
Hyperimmunoglobulin E [IgE] syndrome
Billable
D82.8
Immunodeficiency associated with other specified major defects
Billable
D82.9
Immunodeficiency associated with major defect, unspecified
Billable
D83
Common variable immunodeficiency
D83.0
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
Billable
D83.1
Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
Billable
D83.2
Common variable immunodeficiency with autoantibodies to B- or T-cells
Billable
D83.8
Other common variable immunodeficiencies
Billable
D83.9
Common variable immunodeficiency, unspecified
Billable
D84
Other immunodeficiencies
D84.0
Lymphocyte function antigen-1 [LFA-1] defect
Billable
D84.1
Defects in the complement system
Billable
D84.8
Other specified immunodeficiencies
D84.81
Immunodeficiency due to conditions classified elsewhere
Billable
D84.82
Immunodeficiency due to drugs and external causes
D84.821
Immunodeficiency due to drugs
Billable
D84.822
Immunodeficiency due to external causes
Billable
D84.89
Other immunodeficiencies
Billable
D84.9
Immunodeficiency, unspecified
Billable
D86
Sarcoidosis
D86.0
Sarcoidosis of lung
Billable
D86.1
Sarcoidosis of lymph nodes
Billable
D86.2
Sarcoidosis of lung with sarcoidosis of lymph nodes
Billable
D86.3
Sarcoidosis of skin
Billable
D86.8
Sarcoidosis of other sites
D86.81
Sarcoid meningitis
Billable
D86.82
Multiple cranial nerve palsies in sarcoidosis
Billable
D86.83
Sarcoid iridocyclitis
Billable
D86.84
Sarcoid pyelonephritis
Billable
D86.85
Sarcoid myocarditis
Billable
D86.86
Sarcoid arthropathy
Billable
D86.87
Sarcoid myositis
Billable
D86.89
Sarcoidosis of other sites
Billable
D86.9
Sarcoidosis, unspecified
Billable
D89
Other disorders involving the immune mechanism, not elsewhere classified
D89.0
Polyclonal hypergammaglobulinemia
Billable
D89.1
Cryoglobulinemia
Billable
D89.2
Hypergammaglobulinemia, unspecified
Billable
D89.3
Immune reconstitution syndrome
Billable
D89.4
Mast cell activation syndrome and related disorders
D89.40
Mast cell activation, unspecified
Billable
D89.41
Monoclonal mast cell activation syndrome
Billable
D89.42
Idiopathic mast cell activation syndrome
Billable
D89.43
Secondary mast cell activation
Billable
D89.44
Hereditary alpha tryptasemia
Billable
D89.49
Other mast cell activation disorder
Billable
D89.8
Other specified disorders involving the immune mechanism, not elsewhere classified
D89.81
Graft-versus-host disease
D89.810
Acute graft-versus-host disease
Billable
D89.811
Chronic graft-versus-host disease
Billable
D89.812
Acute on chronic graft-versus-host disease
Billable
D89.813
Graft-versus-host disease, unspecified
Billable
D89.82
Autoimmune lymphoproliferative syndrome [ALPS]
Billable
D89.83
Cytokine release syndrome
D89.831
Cytokine release syndrome, grade 1
Billable
D89.832
Cytokine release syndrome, grade 2
Billable
D89.833
Cytokine release syndrome, grade 3
Billable
D89.834
Cytokine release syndrome, grade 4
Billable
D89.835
Cytokine release syndrome, grade 5
Billable
D89.839
Cytokine release syndrome, grade unspecified
Billable
D89.84
IgG4-related disease
Billable
D89.89
Other specified disorders involving the immune mechanism, not elsewhere classified
Billable
D89.9
Disorder involving the immune mechanism, unspecified
Billable

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Frequently Asked Questions
What are common symptoms of primary immunodeficiency disorders (D80-D89)?

Primary immunodeficiency disorders, classified under ICD-10 codes D80-D89, often present with recurrent infections, chronic fatigue, and delayed growth in children. These symptoms occur due to the immune system's inability to effectively combat pathogens.

How are immune mechanism disorders diagnosed?

Diagnosis of immune mechanism disorders, such as those in the ICD-10 range D80-D89, typically involves a combination of blood tests to assess immune function, genetic testing, and clinical evaluation of symptoms. Early diagnosis is crucial for effective management.

What treatments are available for disorders involving the immune mechanism?

Treatment for disorders involving the immune mechanism, covered under ICD-10 codes D80-D89, may include immunoglobulin replacement therapy, antibiotics for infection management, and in some cases, bone marrow transplantation. Treatment plans are tailored to individual patient needs.