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Therapeutic drug monitoring for narrow therapeutic index medications

Meaning

Measuring serum drug concentrations at intervals to maintain therapeutic levels within a narrow range, optimizing efficacy and minimizing toxicity.

Clinical Context

Used for medications where the therapeutic dose is close to the toxic dose, requiring careful monitoring to ensure patient safety and medication effectiveness.

Example Usage

"Therapeutic drug monitoring will be initiated for digoxin to ensure therapeutic levels and prevent toxicity."

Usage Context

Monitoring of drug levels like digoxin, phenytoin, vancomycin, and certain immunosuppressants.

Related Phrases
Serum drug levels
Therapeutic range
Toxicity monitoring
Pharmacokinetic monitoring

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